PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis

Family

ERF

Protein Properties

Length: 359aa MW: 39338.7 Da PI: 6.8551

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cucsa.064390.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	65.2	1.3e-20	174	223	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr+++ +g+WvAeIr p++ r+r +lg+f+taeeAa a+++a+ kl+g Cucsa.064390.1 174 LYRGVRQRH-WGKWVAEIRLPRN---RTRLWLGTFDTAEEAALAYDKAAFKLRG 223 59****9.******955...5***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.96E-35	173	233	No hit	No description
SuperFamily	SSF54171	4.64E-23	174	231	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	5.6E-33	174	232	IPR001471	AP2/ERF domain
SMART	SM00380	1.4E-40	174	237	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.591	174	231	IPR001471	AP2/ERF domain
Pfam	PF00847	1.6E-14	175	223	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.5E-11	175	186	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.5E-11	197	213	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 359 aa Download sequence Send to blast
MEAAMDFYNE GSQTDHFGGE LMEAIVPFIK VASSSSSSLS TFPSSSSPTP YLSPHYSSSF 60 NTHLNFSHSA SQQSNLYPNG CSTSMNPVFS DGFSTQNLIG FEQPVTIGPH QLSSSQIPHS 120 QPQNNLLQNQ TPLAFAWGQQ NHQPPSSSEQ PPSFLAPKPI PMKQVGSSSK PTKLYRGVRQ 180 RHWGKWVAEI RLPRNRTRLW LGTFDTAEEA ALAYDKAAFK LRGDSARLNF PNLKHQGSCV 240 EGEFGEYRPL HSSVAAKLQA ICDNLAKPQK QGNSKKPVTA AKKSKSQSCS MAEETAAVKV 300 ENSSSRAVTE SDGSEASSPL SDLTFPDFTE MLWDQSQPWE NSMLEKYPSE IDWASILP*

Sequence ? help Back to Top

Protein Sequence Length: 359 aa Download sequence Send to blast

MEAAMDFYNE GSQTDHFGGE LMEAIVPFIK VASSSSSSLS TFPSSSSPTP YLSPHYSSSF  60
NTHLNFSHSA SQQSNLYPNG CSTSMNPVFS DGFSTQNLIG FEQPVTIGPH QLSSSQIPHS  120
QPQNNLLQNQ TPLAFAWGQQ NHQPPSSSEQ PPSFLAPKPI PMKQVGSSSK PTKLYRGVRQ  180
RHWGKWVAEI RLPRNRTRLW LGTFDTAEEA ALAYDKAAFK LRGDSARLNF PNLKHQGSCV  240
EGEFGEYRPL HSSVAAKLQA ICDNLAKPQK QGNSKKPVTA AKKSKSQSCS MAEETAAVKV  300
ENSSSRAVTE SDGSEASSPL SDLTFPDFTE MLWDQSQPWE NSMLEKYPSE IDWASILP*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	7e-22	173	231	1	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681867	0.0	LN681867.1 Cucumis melo genomic scaffold, anchoredscaffold00013.
GenBank	LN713261	0.0	LN713261.1 Cucumis melo genomic chromosome, chr_7.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004142609.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-13-like
Swissprot	Q8H1E4	3e-77	RAP24_ARATH; Ethylene-responsive transcription factor RAP2-4
TrEMBL	A0A0A0L0N8	0.0	A0A0A0L0N8_CUCSA; Uncharacterized protein
STRING	XP_004142609.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1057	32	109

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G78080.1	2e-62	related to AP2 4

Link Out ? help Back to Top
Phytozome	Cucsa.064390.1
Entrez Gene	101214560

Publications ? help Back to Top
Pati A,Vasquez-Robinet C,Heath LS,Grene R,Murali TM XcisClique: analysis of regulatory bicliques. BMC Bioinformatics, 2006. 7: p. 218 [PMID:16630346] Ren Y, et al. An integrated genetic and cytogenetic map of the cucumber genome. PLoS ONE, 2009. 4(6): p. e5795 [PMID:19495411] Guo S, et al. Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics, 2010. 11: p. 384 [PMID:20565788] Li Z, et al. RNA-Seq improves annotation of protein-coding genes in the cucumber genome. BMC Genomics, 2011. 12: p. 540 [PMID:22047402] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Iwase A, et al. WIND1-based acquisition of regeneration competency in Arabidopsis and rapeseed. J. Plant Res., 2015. 128(3): p. 389-97 [PMID:25810222] Ikeuchi M, et al. PRC2 represses dedifferentiation of mature somatic cells in Arabidopsis. Nat Plants, 2015. 1: p. 15089 [PMID:27250255] Iwase A, et al. WIND1 Promotes Shoot Regeneration through Transcriptional Activation of ENHANCER OF SHOOT REGENERATION1 in Arabidopsis. Plant Cell, 2017. 29(1): p. 54-69 [PMID:28011694]