PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cla008346

Organism

Citrullus lanatus

Taxonomic ID

3654

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Citrullus

Family

WRKY

Protein Properties

Length: 594aa MW: 64179 Da PI: 8.0204

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cla008346	genome	ICuGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	93.8	1.3e-29	255	314	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt + +C v+k+v+r+a+d +++++tYeg+Hnh+ Cla008346 255 MNDGCQWRKYGQKIAKGNPCPRAYYRCTGSpTCLVRKQVQRCADDMSILITTYEGNHNHP 314 58************************888**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	7.0E-31	241	316	IPR003657	WRKY domain
SuperFamily	SSF118290	1.11E-26	248	316	IPR003657	WRKY domain
PROSITE profile	PS50811	28.564	250	316	IPR003657	WRKY domain
SMART	SM00774	1.1E-35	255	315	IPR003657	WRKY domain
Pfam	PF03106	7.6E-26	256	314	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 594 aa Download sequence Send to blast
MEAAAAPFGC PRPVVKTEKP AGDGDNNQDS PSKQHLLVKR GNYAKQEHEA EDKSNSSDQK 60 DLSCTNLQEK QLESARAEMG EVREENQRLK KSLNQIMKDY EALKMQFLGI VGQESKKFPN 120 QDDMSNKEQQ HDQIELVSLT LGRFPVAEKK KTADEKNSVN IIIGGNDEEA AVKEALSLGL 180 NCKFKHEESI MTVAVKDVDS PKSFDHEMRE EAGETNWSST KGAKTIRSVE DDVTPQNPPK 240 RARVCVRARC ETATMNDGCQ WRKYGQKIAK GNPCPRAYYR CTGSPTCLVR KQVQRCADDM 300 SILITTYEGN HNHPLPASAN AMASTTSAAA SMLLSGSSTS TAASSSSTNT NNLQGLNFYT 360 NNSKPNFYLP NNSSIISSTS PTHPTITLDL TSNPSSSSSN CSTHFGKFTS SFPNSRYPFT 420 SQLDFGSSRN NVLSWNNGLL SYNRNNHQTT TTTTNNIYQN YIQQRNPATS LPHQQPPLPD 480 TIAAATKAIT ADPSFQSALA AALTSIISTG GASAGPTKST SARGEQSLFQ LMAATTTNKG 540 NGCGTSFLNN ITTSTTTSNS PPTGNMVFVP ASSLPFSSSK SASASPGDHI DLTN

Sequence ? help Back to Top

Protein Sequence Length: 594 aa Download sequence Send to blast

MEAAAAPFGC PRPVVKTEKP AGDGDNNQDS PSKQHLLVKR GNYAKQEHEA EDKSNSSDQK  60
DLSCTNLQEK QLESARAEMG EVREENQRLK KSLNQIMKDY EALKMQFLGI VGQESKKFPN  120
QDDMSNKEQQ HDQIELVSLT LGRFPVAEKK KTADEKNSVN IIIGGNDEEA AVKEALSLGL  180
NCKFKHEESI MTVAVKDVDS PKSFDHEMRE EAGETNWSST KGAKTIRSVE DDVTPQNPPK  240
RARVCVRARC ETATMNDGCQ WRKYGQKIAK GNPCPRAYYR CTGSPTCLVR KQVQRCADDM  300
SILITTYEGN HNHPLPASAN AMASTTSAAA SMLLSGSSTS TAASSSSTNT NNLQGLNFYT  360
NNSKPNFYLP NNSSIISSTS PTHPTITLDL TSNPSSSSSN CSTHFGKFTS SFPNSRYPFT  420
SQLDFGSSRN NVLSWNNGLL SYNRNNHQTT TTTTNNIYQN YIQQRNPATS LPHQQPPLPD  480
TIAAATKAIT ADPSFQSALA AALTSIISTG GASAGPTKST SARGEQSLFQ LMAATTTNKG  540
NGCGTSFLNN ITTSTTTSNS PPTGNMVFVP ASSLPFSSSK SASASPGDHI DLTN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	2e-20	246	317	8	78	Probable WRKY transcription factor 4
2lex_A	2e-20	246	317	8	78	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681932	0.0	LN681932.1 Cucumis melo genomic scaffold, anchoredscaffold00001.
GenBank	LN713266	0.0	LN713266.1 Cucumis melo genomic chromosome, chr_12.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004152535.1	0.0	PREDICTED: probable WRKY transcription factor 61
Swissprot	A0A3Q7GFB5	1e-116	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1S3ATY0	0.0	A0A1S3ATY0_CUCME; probable WRKY transcription factor 61
STRING	XP_004165456.1	0.0	(Cucumis sativus)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF650	34	134

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	3e-59	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]