PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ciclev10016511m
Common NameCICLE_v10016511mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family bHLH
Protein Properties Length: 236aa    MW: 25755.3 Da    PI: 7.2963
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ciclev10016511mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH29.21.7e-0979125554
                      HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
              HLH   5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                      +  rE+ RRdr+N++f eL ++l +    + +K++K   L  Av+ + +L
  Ciclev10016511m  79 KACREKMRRDRLNDRFMELASILDPG---RPPKMDKTVLLADAVQMVTQL 125
                      678**********************8...88**************99988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088812.29774125IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.12E-778130No hitNo description
PfamPF000104.0E-778125IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.9E-880131IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.79E-1280153IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.2E-1181135IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:1.20.5.10003.5E-5136175No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 236 aa     Download sequence    Send to blast
MSSPYNSNWI FDCGLLDGIG VSGGDLPSLD PPEVLWSSST SNPPLSAEFD DSFGNLDAFK  60
ETGSRKRVRS GSCSASGSKA CREKMRRDRL NDRFMELASI LDPGRPPKMD KTVLLADAVQ  120
MVTQLRDEAQ KLKVSNENLL GKINELKCEK NELRDEKQRL KNEKENLERQ VKALSSQPAF  180
LPHPPPVPAP FSAPGQVVGG KLVPLVGYPG VSMWQFMPPA AVDTSQDHVL RPPVA*
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269|PubMed:17028341}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269|PubMed:17028341}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006449136.11e-172transcription factor ILR3
SwissprotQ9FH371e-88ILR3_ARATH; Transcription factor ILR3
TrEMBLA0A2H5N2U41e-171A0A2H5N2U4_CITUN; Uncharacterized protein
TrEMBLV4UJ841e-171V4UJ84_9ROSI; Uncharacterized protein
STRINGXP_006449136.11e-171(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM14372890
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G54680.13e-74bHLH family protein
Publications ? help Back to Top
  1. Li X,Zhang H,Ai Q,Liang G,Yu D
    Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.
    Plant Physiol., 2016. 170(4): p. 2478-93
    [PMID:26921305]
  2. Aparicio F,Pallás V
    The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response.
    Mol. Plant Pathol., 2017. 18(2): p. 173-186
    [PMID:26929142]
  3. Liang G,Zhang H,Li X,Ai Q,Yu D
    bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1743-1755
    [PMID:28369511]
  4. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]
  7. Samira R, et al.
    The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis.
    Plant Mol. Biol., 2018. 97(4-5): p. 297-309
    [PMID:29882068]