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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
Ciclev10011656m |
| Common Name | CICLE_v10011632mg |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
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| Family |
E2F/DP |
| Protein Properties |
Length: 471aa MW: 52341.6 Da PI: 4.8948 |
| Description |
E2F/DP family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| Ciclev10011656m | genome | ICGC | View CDS |
|
| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | E2F_TDP | 86.2 | 2.5e-27 | 146 | 211 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg
Ciclev10011656m 146 RYDSSLGLLTKKFINLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 211
6899******************************...99..****************************98 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
| GO:0051446 | Biological Process | positive regulation of meiotic cell cycle |
| GO:0005634 | Cellular Component | nucleus |
| GO:0005667 | Cellular Component | transcription factor complex |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 471 aa
Download sequence Send
to blast |
MSGASRAPYR TAPPPPNPPR SGPIVPPIKR HLAFVTTKPP FVPSDDYHRF SNTRRAADQE 60
PEAIVVRSPQ LKRKNGMEDN EVETSEWVGS PGLTNISNGP FHTPVSAKGG RVNNRSKGIK 120
GNRSTPQTPV SNAGSPSALT PAGSCRYDSS LGLLTKKFIN LIKHAEDGIL DLNKAAETLE 180
VQKRRIYDIT NVLEGIGLIE KKLKNRIRWK GLDNSIPGEV DADASILQAD IDNLSMEELR 240
VDEQTRELRE RLRELIENEN NRKWLFVTEE DIKNLHCFQN QTLIAIKAPQ GTTLEVPDPD 300
EAVDYPQRRY RIILRSTMGP IDVYLVSRFE EKFEETNSVE PPASVPPVSS SDSNENQVKE 360
IINVDRAGNE TEAQAQQAHQ IYSDLNSSQE VVGGMMKIVP SDVDNDADYW LLSDADVSIT 420
DMWKTDCAEW DGVNMLHAEF GMSDACTPTP QTPPSRITEV PSTDFNPIHR *
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}. |
| Uniprot | TISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}. |
| Functional Description ? help
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| Source |
Description |
| UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
