PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

CCG016961.1

Organism

Populus euphratica

Taxonomic ID

75702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus

Family

E2F/DP

Protein Properties

Length: 502aa MW: 56033.5 Da PI: 5.0944

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
CCG016961.1	genome	LZU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.2	2.5e-27	151	216	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg CCG016961.1 151 RYDSSLGLLTKKFINLIKRAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 216 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46785	7.48E-17	151	214	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	3.8E-28	151	217	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.9E-34	151	216	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.1E-24	153	216	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	4.64E-43	228	334	No hit	No description
SuperFamily	SSF144074	3.92E-30	230	334	No hit	No description
Pfam	PF16421	1.8E-30	233	332	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 502 aa Download sequence Send to blast
MSNSQAPNNQ SMKQPQQNSM QSHAPNQCQQ HQQLSFSSMK PHFLPPGDYH RFGVDHRRPV 60 SDHDVEGIVV KPPTLKRKSD AADHQGESSE WNAGHGYMEV VTSPLQTPVS GKGGKTPKTS 120 RLSRSGKSAS QSAAGALGSP GNNVTPTGPI RYDSSLGLLT KKFINLIKRA EDGILDLNKA 180 ADTLEVQKRR IYDITNVLEG IGLIEKKLKN RIQWKGHDVS RPREGDGNNV ATLQAEVENL 240 TIEERRLDEQ TREMQERLRD LSVDEKNQKW LFVTKEDIKI LPGFQNETLI AIKAPHGTTL 300 EVPDPDEAVD YPQRRYRIVF RSTMGPIDVY LVSQFEEKFE DIQGAEPPPS DSSTLVFNEN 360 PATTMVTEES RAKEFEMQEQ DGHRMCSELN TSHDFKDARC QLLLFAGNVN NTCKHIQLSM 420 MDRDSTLCSD NCLEISDADY WLLSDADVSI TDISLTAKIA VVEWNDLDTL HNDYVIPDFS 480 TPQPQTPSNP TEVPPAANTT AG

Sequence ? help Back to Top

Protein Sequence Length: 502 aa Download sequence Send to blast

MSNSQAPNNQ SMKQPQQNSM QSHAPNQCQQ HQQLSFSSMK PHFLPPGDYH RFGVDHRRPV  60
SDHDVEGIVV KPPTLKRKSD AADHQGESSE WNAGHGYMEV VTSPLQTPVS GKGGKTPKTS  120
RLSRSGKSAS QSAAGALGSP GNNVTPTGPI RYDSSLGLLT KKFINLIKRA EDGILDLNKA  180
ADTLEVQKRR IYDITNVLEG IGLIEKKLKN RIQWKGHDVS RPREGDGNNV ATLQAEVENL  240
TIEERRLDEQ TREMQERLRD LSVDEKNQKW LFVTKEDIKI LPGFQNETLI AIKAPHGTTL  300
EVPDPDEAVD YPQRRYRIVF RSTMGPIDVY LVSQFEEKFE DIQGAEPPPS DSSTLVFNEN  360
PATTMVTEES RAKEFEMQEQ DGHRMCSELN TSHDFKDARC QLLLFAGNVN NTCKHIQLSM  420
MDRDSTLCSD NCLEISDADY WLLSDADVSI TDISLTAKIA VVEWNDLDTL HNDYVIPDFS  480
TPQPQTPSNP TEVPPAANTT AG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-25	146	216	2	73	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY179506	0.0	AY179506.1 Populus alba E2F mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011043212.1	0.0	PREDICTED: transcription factor E2FB-like
Swissprot	Q9FV71	1e-136	E2FB_ARATH; Transcription factor E2FB
TrEMBL	B9HQ23	0.0	B9HQ23_POPTR; Uncharacterized protein
STRING	POPTR_0009s16350.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1947	34	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-125	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]