PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Achn349821
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia
Family C2H2
Protein Properties Length: 284aa    MW: 32024.3 Da    PI: 7.5351
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Achn349821genomeIKGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.22.9e-057698123
                EEETTTTEEESSHHHHHHHHHHT CS
     zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                y C+ C+k F r  nL+ H r H
  Achn349821 76 YICEVCHKGFQRDQNLQLHRRGH 98
                89*******************88 PP

2zf-C2H211.30.0011152174123
                 EEETTTTEEESSHHHHHHHHHHT CS
     zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                 +kC +C k++  +s+ k H + +
  Achn349821 152 WKCDKCAKRYAVQSDWKAHAKIC 174
                 58*****************9987 PP

3zf-C2H212.30.00052182200523
                 TTTEEESSHHHHHHHHHHT CS
     zf-C2H2   5 dCgksFsrksnLkrHirtH 23 
                 dCg+ Fsrk+++++H   +
  Achn349821 182 DCGTIFSRKDSFVTHRAFC 200
                 9**************8765 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.2E-57598IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.5E-67598No hitNo description
SMARTSM003550.0387698IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.7417698IPR007087Zinc finger, C2H2
PROSITE patternPS0002807898IPR007087Zinc finger, C2H2
SMARTSM00355140117147IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.608.9E-5139173IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.5E-6147172No hitNo description
SMARTSM00355210152172IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 284 aa     Download sequence    Send to blast
MTLKLVDLGG GEASWGGRDG GGRTGIVELE MWLRVEFEED LDDEQLHNGS PNHTENDPEA  60
EVVTLSPRTL MATNRYICEV CHKGFQRDQN LQLHRRGHNL PWKPKQRPTT QVKKRVYICP  120
EPNCVHHDPS RALGDLSGIK KHFCRKHGEK KWKCDKCAKR YAVQSDWKAH AKICGTREYL  180
CDCGTIFSRK DSFVTHRAFC DALTEENYKM NQTLAAAGGM MPHNSHQELF SSSMLVSDSN  240
TIMNLSNPHD NSIDNIPLKP LCLNSHGAML SSDLDPIFNP RMP*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C2e-34148211366Zinc finger protein JACKDAW
5b3h_F2e-34148211366Zinc finger protein JACKDAW
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
11521GGRDGGG
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269|PubMed:25035403}.
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027166639.11e-133zinc finger protein GAI-ASSOCIATED FACTOR 1-like
SwissprotQ9SCQ65e-96IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
SwissprotQ9ZWA61e-95IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A2R6QRJ50.0A0A2R6QRJ5_ACTCH; Protein indeterminate-domain like
STRINGXP_002512692.11e-130(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA1590056
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G50700.18e-99indeterminate(ID)-domain 2
Publications ? help Back to Top
  1. Fukazawa J, et al.
    DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2920-38
    [PMID:25035403]
  2. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  3. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]
  4. Khare D, et al.
    Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana.
    New Phytol., 2017. 213(3): p. 1257-1273
    [PMID:27768815]