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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
AT5G48150.2 |
Common Name | MIF21.4, PAT1 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Family |
GRAS |
Protein Properties |
Length: 490aa MW: 55290.1 Da PI: 6.584 |
Description |
GRAS family protein |
Gene Model |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | GRAS | 462.5 | 2.5e-141 | 120 | 490 | 2 | 374 |
GRAS 2 velLlecAeavssgdlelaqalLarlselaspdgdpmqRlaayfteALaarlarsvselykalppsetseknsseelaalklfsevsPilkfshltaN 99
+ L++cA+a+s++dl +a++++++l++++s +g+p+qRl ay++e+L a+la+s+s++ykal+ +++ s+e l+++++++ev+P++kf+++ aN
AT5G48150.2 120 RADLVSCAKAMSENDLMMAHSMMEKLRQMVSVSGEPIQRLGAYLLEGLVAQLASSGSSIYKALNRCPEP--ASTELLSYMHILYEVCPYFKFGYMSAN 215
678************************************************************666665..499************************ PP
GRAS 100 qaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesg..skeeleetgerLakfAeelgvpfefnvlvakrledleleeLr 195
aI ea+++e+rvHiiDf+i+qG QW++L+qa+a+Rp+gpp++RiTg+++++s + l+ +g+rLak+A++++vpfefn v+ +++++++++L
AT5G48150.2 216 GAIAEAMKEENRVHIIDFQIGQGSQWVTLIQAFAARPGGPPRIRITGIDDMTSAyaRGGGLSIVGNRLAKLAKQFNVPFEFNS-VSVSVSEVKPKNLG 312
**************************************************999999999************************.7999********** PP
GRAS 196 vkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsleaklpreseerikvErellgre 293
v+pgEalaVn+++ lh+++desvs+e++rd++L++vkslsPkvv++veqe+++n++ F+ rf+e+++yy+a+f+s++++lpr++++ri+vE+++l+r+
AT5G48150.2 313 VRPGEALAVNFAFVLHHMPDESVSTENHRDRLLRMVKSLSPKVVTLVEQESNTNTAAFFPRFMETMNYYAAMFESIDVTLPRDHKQRINVEQHCLARD 410
************************************************************************************************** PP
GRAS 294 ivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdgyrveeesgslvlgWkdrpLvsvSaWr 374
+vn++acega+r+erhe l+kWr+r+++aGF+p+pls +++++k+llr+++++ yr+ee++g+l+lgW++r Lv+ +aW+
AT5G48150.2 411 VVNIIACEGADRVERHELLGKWRSRFGMAGFTPYPLSPLVNSTIKSLLRNYSDK-YRLEERDGALYLGWMHRDLVASCAWK 490
****************************************************55.*************************8 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
GO:0007165 | Biological Process | signal transduction |
GO:0009640 | Biological Process | photomorphogenesis |
GO:0005634 | Cellular Component | nucleus |
GO:0005737 | Cellular Component | cytoplasm |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
GO:0004871 | Molecular Function | signal transducer activity |
GO:0043565 | Molecular Function | sequence-specific DNA binding |
Sequence ? help Back to Top |
Protein Sequence Length: 490 aa
Download sequence Send
to blast |
MYKQPRQELE AYYFEPNSVE KLRYLPVNNS RKRFCTLEPF PDSPPYNALS TATYDDTCGS 60 CVTDELNDFK HKIREIETVM MGPDSLDLLV DCTDSFDSTA SQEINGWRST LEAISRRDLR 120 ADLVSCAKAM SENDLMMAHS MMEKLRQMVS VSGEPIQRLG AYLLEGLVAQ LASSGSSIYK 180 ALNRCPEPAS TELLSYMHIL YEVCPYFKFG YMSANGAIAE AMKEENRVHI IDFQIGQGSQ 240 WVTLIQAFAA RPGGPPRIRI TGIDDMTSAY ARGGGLSIVG NRLAKLAKQF NVPFEFNSVS 300 VSVSEVKPKN LGVRPGEALA VNFAFVLHHM PDESVSTENH RDRLLRMVKS LSPKVVTLVE 360 QESNTNTAAF FPRFMETMNY YAAMFESIDV TLPRDHKQRI NVEQHCLARD VVNIIACEGA 420 DRVERHELLG KWRSRFGMAG FTPYPLSPLV NSTIKSLLRN YSDKYRLEER DGALYLGWMH 480 RDLVASCAWK
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Functional Description ? help
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Source |
Description |
TAIR | Member of GRAS gene family. Semi-dominant mutant has a reduced response to far-red light and appears to act early in the phytochrome A signaling pathway. |
UniProt | Probable transcription factor involved in phytochrome A (phyA) signal transduction. {ECO:0000269|PubMed:10817761}. |
Function -- GeneRIF ? help
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- Both PAT1 and SCL21 are involved in phyA-dependent signaling.
[PMID: 23109688] - The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2.
[PMID: 25603932] - The heterodimeric transcription factor complex ETHYLENE RESPONSE FACTOR115 (ERF115)-PHYTOCHROME A SIGNAL TRANSDUCTION1 (PAT1) sustains meristem function by promoting cell renewal after stem cell loss.
[PMID: 27797356]
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Phenotype -- Disruption Phenotype ? help
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Source |
Description |
UniProt | DISRUPTION PHENOTYPE: Plants display reduced response to far-red (FR) light. Seedlings develop long hypocotyls, unfolded cotyledons, no significant anthocyanin accumulation, and greening after FR light. {ECO:0000269|PubMed:10817761}. |
Annotation --
Nucleotide ? help
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Source |
Hit ID |
E-value |
Description |
GenBank | AF153443 | 0.0 | AF153443.1 Arabidopsis thaliana phytochrome A signal transduction 1 protein (PAT1) mRNA, complete cds. |
GenBank | AK317252 | 0.0 | AK317252.1 Arabidopsis thaliana AT5G48150 mRNA, complete cds, clone: RAFL22-43-D17. |
GenBank | AK317747 | 0.0 | AK317747.1 Arabidopsis thaliana AT5G48150 mRNA, complete cds, clone: RAFL22-04-F15. |
GenBank | BT025326 | 0.0 | BT025326.1 Arabidopsis thaliana At5g48150 mRNA, complete cds. |
Publications
? help Back to Top |
- Bolle C,Koncz C,Chua NH
PAT1, a new member of the GRAS family, is involved in phytochrome A signal transduction. Genes Dev., 2000. 14(10): p. 1269-78 [PMID:10817761] - Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] - Seki M, et al.
Functional annotation of a full-length Arabidopsis cDNA collection. Science, 2002. 296(5565): p. 141-5 [PMID:11910074] - McCormac AC,Terry MJ
Light-signalling pathways leading to the co-ordinated expression of HEMA1 and Lhcb during chloroplast development in Arabidopsis thaliana. Plant J., 2002. 32(4): p. 549-59 [PMID:12445126] - Tian C,Wan P,Sun S,Li J,Chen M
Genome-wide analysis of the GRAS gene family in rice and Arabidopsis. Plant Mol. Biol., 2004. 54(4): p. 519-32 [PMID:15316287] - Brenner WG,Romanov GA,K
Immediate-early and delayed cytokinin response genes of Arabidopsis thaliana identified by genome-wide expression profiling reveal novel cytokinin-sensitive processes and suggest cytokinin action through transcriptional cascades. Plant J., 2005. 44(2): p. 314-33 [PMID:16212609] - Duarte JM, et al.
Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] - Torres-Galea P,Huang LF,Chua NH,Bolle C
The GRAS protein SCL13 is a positive regulator of phytochrome-dependent red light signaling, but can also modulate phytochrome A responses. Mol. Genet. Genomics, 2006. 276(1): p. 13-30 [PMID:16680434] - Lee MH, et al.
Large-scale analysis of the GRAS gene family in Arabidopsis thaliana. Plant Mol. Biol., 2008. 67(6): p. 659-70 [PMID:18500650] - Klopffleisch K, et al.
Arabidopsis G-protein interactome reveals connections to cell wall carbohydrates and morphogenesis. Mol. Syst. Biol., 2011. 7: p. 532 [PMID:21952135] - Meinke DW
A survey of dominant mutations in Arabidopsis thaliana. Trends Plant Sci., 2013. 18(2): p. 84-91 [PMID:22995285] - Torres-Galea P,Hirtreiter B,Bolle C
Two GRAS proteins, SCARECROW-LIKE21 and PHYTOCHROME A SIGNAL TRANSDUCTION1, function cooperatively in phytochrome A signal transduction. Plant Physiol., 2013. 161(1): p. 291-304 [PMID:23109688] - Ding Y, et al.
Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] - Roux ME, et al.
The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2. EMBO J., 2015. 34(5): p. 593-608 [PMID:25603932] - Heyman J, et al.
The heterodimeric transcription factor complex ERF115-PAT1 grants regeneration competence. Nat Plants, 2016. 2(11): p. 16165 [PMID:27797356]
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