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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
AT5G08130.1 |
Common Name | BIM1 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Family |
bHLH |
Protein Properties |
Length: 409aa MW: 45545.4 Da PI: 7.2412 |
Description |
bHLH family protein |
Gene Model |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | HLH | 56.1 | 6.7e-18 | 158 | 207 | 2 | 55 |
HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
r +h++ E+rRR++iN++f+ Lr+l+P++ ++K +Ka+ L +++eYI+ Lq
AT5G08130.1 158 RSKHSATEQRRRSKINDRFQMLRQLIPNS----DQKRDKASFLLEVIEYIQFLQ 207
889*************************9....9*******************9 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0006351 | Biological Process | transcription, DNA-templated |
GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
GO:0009742 | Biological Process | brassinosteroid mediated signaling pathway |
GO:1902448 | Biological Process | positive regulation of shade avoidance |
GO:0005634 | Cellular Component | nucleus |
GO:0003677 | Molecular Function | DNA binding |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
GO:0005515 | Molecular Function | protein binding |
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
Protein Sequence Length: 409 aa
Download sequence Send
to blast |
MMFNANERNV LDENSNSNCS SYAAASSGFT LWDESASGKK GQTRKENSVG ERVNMRADVA 60 ATVGQWPVAE RRSQSLTNNH MSGFSSLSSS QGSVLKSQSF MDMIRSAKGS SQEDDLDDEE 120 DFIMKKESSS TSQSHRVDLR VKADVRGSPN DQKLNTPRSK HSATEQRRRS KINDRFQMLR 180 QLIPNSDQKR DKASFLLEVI EYIQFLQEKA DKYVTSYQGW NHEPAKLLNW QSNNNQQLVP 240 EGVAFAPKLE EEKNNIPVSV LATAQGVVID HPTTATTSPF PLSIQSNSFF SPVIAGNPVP 300 QFHARVASSE AVEPSPSSRS QKEEEDEEVL EGNIRISSVY SQGLVKTLRE ALENSGVDLT 360 KASISVEIEL AKQSSSSSFK DHEVREPVSR TRNDNVKQTR KPKRLKTGQ
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Expression --
Description ? help
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Source |
Description |
Uniprot | TISSUE SPECIFICITY: Expressed constitutively in roots. {ECO:0000269|PubMed:12679534}. |
Functional Description ? help
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Source |
Description |
TAIR | Arabidopsis thaliana basic helix-loop-helix (bHLH) family protein involved in brassinosteroid signaling. It synergistically interacts with BES1 to bind to E box sequences (CANNTG). |
UniProt | Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation. {ECO:0000269|PubMed:15680330}. |
Function -- GeneRIF ? help
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- role of BIM1 in embryonic development not only implicates a function for brassinosteroids in this process, but the interaction of BIM1 with DRN, involved with auxin signalling, represents a possible point of hormonal crosstalk in embryonic patterning
[PMID: 18830673] - UVR8-BES1/BIM1 interaction represents an early photoreceptor signaling mechanism in plants and serves as an important module integrating light and brassinosteroid signaling
[PMID: 29398622]
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Regulation -- Description ? help
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Source |
Description |
UniProt | INDUCTION: Repressed by cold treatment. {ECO:0000269|PubMed:12679534}. |
Interaction -- BIND ? help
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Source |
Intact With |
Description |
BIND | AT1G19350 | An unspecified isoform of BES1 interacts with BIM1. |
Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] - Yin Y, et al.
BES1 accumulates in the nucleus in response to brassinosteroids to regulate gene expression and promote stem elongation. Cell, 2002. 109(2): p. 181-91 [PMID:12007405] - R
Rapid identification of Arabidopsis insertion mutants by non-radioactive detection of T-DNA tagged genes. Plant J., 2002. 32(2): p. 243-53 [PMID:12383089] - Heim MA, et al.
The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] - Toledo-Ortiz G,Huq E,Quail PH
The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] - Bailey PC, et al.
Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] - Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes. Plant J., 2004. 38(2): p. 366-79 [PMID:15078338] - Yin Y, et al.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis. Cell, 2005. 120(2): p. 249-59 [PMID:15680330] - Gao M,Li G,McCombie WR,Quiros CF
Comparative analysis of a transposon-rich Brassica oleracea BAC clone with its corresponding sequence in A. thaliana. Theor. Appl. Genet., 2005. 111(5): p. 949-55 [PMID:16044267] - Ohashi-Ito K,Bergmann DC
Regulation of the Arabidopsis root vascular initial population by LONESOME HIGHWAY. Development, 2007. 134(16): p. 2959-68 [PMID:17626058] - Gampala SS, et al.
An essential role for 14-3-3 proteins in brassinosteroid signal transduction in Arabidopsis. Dev. Cell, 2007. 13(2): p. 177-89 [PMID:17681130] - Catala R, et al.
The Arabidopsis E3 SUMO ligase SIZ1 regulates plant growth and drought responses. Plant Cell, 2007. 19(9): p. 2952-66 [PMID:17905899] - Chandler JW,Cole M,Flier A,Werr W
BIM1, a bHLH protein involved in brassinosteroid signalling, controls Arabidopsis embryonic patterning via interaction with DORNROSCHEN and DORNROSCHEN-LIKE. Plant Mol. Biol., 2009. 69(1-2): p. 57-68 [PMID:18830673] - Oh E, et al.
Genome-wide analysis of genes targeted by PHYTOCHROME INTERACTING FACTOR 3-LIKE5 during seed germination in Arabidopsis. Plant Cell, 2009. 21(2): p. 403-19 [PMID:19244139] - Elrouby N,Coupland G
Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(40): p. 17415-20 [PMID:20855607] - Efroni I, et al.
Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] - Cifuentes-Esquivel N, et al.
The bHLH proteins BEE and BIM positively modulate the shade avoidance syndrome in Arabidopsis seedlings. Plant J., 2013. 75(6): p. 989-1002 [PMID:23763263] - Jin J, et al.
An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] - Liang T, et al.
UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Dev. Cell, 2018. 44(4): p. 512-523.e5 [PMID:29398622]
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