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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
AT1G35460.1 |
Common Name | BHLH80, EN71, F12A4.2, FBH1 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Family |
bHLH |
Protein Properties |
Length: 259aa MW: 28526.6 Da PI: 5.2259 |
Description |
bHLH family protein |
Gene Model |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | HLH | 40.5 | 4.8e-13 | 193 | 238 | 6 | 55 |
HHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 6 nerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
+++Er RR ri +++ +L+el+P+ +k + a++Le+AveY+k Lq
AT1G35460.1 193 SIAERVRRTRISDRIRRLQELVPNM----DKQTNTADMLEEAVEYVKALQ 238
689*********************7....688*****************9 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0042335 | Biological Process | cuticle development |
GO:0045944 | Biological Process | positive regulation of transcription from RNA polymerase II promoter |
GO:0005634 | Cellular Component | nucleus |
GO:0001046 | Molecular Function | core promoter sequence-specific DNA binding |
GO:0001228 | Molecular Function | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding |
GO:0005515 | Molecular Function | protein binding |
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
Protein Sequence Length: 259 aa
Download sequence Send
to blast |
MQSTHISGGS SGGGGGGGGE VSRSGLSRIR SAPATWIETL LEEDEEEGLK PNLCLTELLT 60 GNNNSGGVIT SRDDSFEFLS SVEQGLYNHH QGGGFHRQNS SPADFLSGSG SGTDGYFSNF 120 GIPANYDYLS TNVDISPTKR SRDMETQFSS QLKEEQMSGG ISGMMDMNMD KIFEDSVPCR 180 VRAKRGCATH PRSIAERVRR TRISDRIRRL QELVPNMDKQ TNTADMLEEA VEYVKALQSQ 240 IQELTEQQKR CKCKPKEEQ
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Expression --
Description ? help
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Source |
Description |
Uniprot | TISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}. |
Function -- GeneRIF ? help
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- There are four CONSTANS transcriptional activators FBH1-4 which are related basic helix-loop-helix-type transcription factors that preferentially bind to the E-box cis-elements in the CO promoter. Overexpression of all FBH genes drastically elevated CO levels and caused early flowering regardless of photoperiod. [FBH1]
[PMID: 22334645] - Results indicate a role for FLOWERING BASIC HELIX-LOOP-HELIX 1 (FBH1, AT1G35460) as a transcriptional modulator of warm temperature signals and clock responses.
[PMID: 25246594]
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Annotation --
Nucleotide ? help
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Source |
Hit ID |
E-value |
Description |
GenBank | AF411791 | 0.0 | AF411791.1 Arabidopsis thaliana At1g35460/F12A4_2 mRNA, complete cds. |
GenBank | AY093794 | 0.0 | AY093794.1 Arabidopsis thaliana At1g35460/F12A4_2 mRNA, complete cds. |
Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] - Heim MA, et al.
The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] - Toledo-Ortiz G,Huq E,Quail PH
The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] - Yamada K, et al.
Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] - Bailey PC, et al.
Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] - Nawy T, et al.
Transcriptional profile of the Arabidopsis root quiescent center. Plant Cell, 2005. 17(7): p. 1908-25 [PMID:15937229] - Kuusk S,Sohlberg JJ,Magnus Eklund D,Sundberg E
Functionally redundant SHI family genes regulate Arabidopsis gynoecium development in a dose-dependent manner. Plant J., 2006. 47(1): p. 99-111 [PMID:16740146] - Panjabi P, et al.
Comparative mapping of Brassica juncea and Arabidopsis thaliana using Intron Polymorphism (IP) markers: homoeologous relationships, diversification and evolution of the A, B and C Brassica genomes. BMC Genomics, 2008. 9: p. 113 [PMID:18315867] - Elrouby N,Coupland G
Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(40): p. 17415-20 [PMID:20855607] - Ito S, et al.
FLOWERING BHLH transcriptional activators control expression of the photoperiodic flowering regulator CONSTANS in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2012. 109(9): p. 3582-7 [PMID:22334645] - Efroni I, et al.
Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] - Nagel DH,Pruneda-Paz JL,Kay SA
FBH1 affects warm temperature responses in the Arabidopsis circadian clock. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(40): p. 14595-600 [PMID:25246594] - Li S, et al.
CFLAP1 and CFLAP2 Are Two bHLH Transcription Factors Participating in Synergistic Regulation of AtCFL1-Mediated Cuticle Development in Arabidopsis. PLoS Genet., 2016. 12(1): p. e1005744 [PMID:26745719]
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