PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

678456708

Organism

Utricularia gibba

Taxonomic ID

13748

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Utricularia

Family

MYB_related

Protein Properties

Length: 436aa MW: 49451.4 Da PI: 6.354

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
678456708	genome	UGSP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	25.2	3.8e-08	108	141	4	36
S-HHHHHHHHHHHHHTTTT-HHHHHHHHT.TTS- CS Myb_DNA-binding 4 WTteEdellvdavkqlGggtWktIartmg.kgRt 36 W ++E+ ll+++++++G g+W+ + +++g k+R+ 678456708 108 WNADEEMLLLEGIEMYGLGNWNQVGEHVGtKNRS 141 *****************************66665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00291	3.5E-9	44	89	IPR000433	Zinc finger, ZZ-type
Pfam	PF00569	6.3E-11	47	89	IPR000433	Zinc finger, ZZ-type
PROSITE profile	PS50135	10.801	48	91	IPR000433	Zinc finger, ZZ-type
SuperFamily	SSF57850	6.47E-14	48	111	No hit	No description
CDD	cd02335	3.30E-23	48	96	No hit	No description
PROSITE pattern	PS01357	0	50	77	IPR000433	Zinc finger, ZZ-type
PROSITE profile	PS51293	13.57	103	151	IPR017884	SANT domain
SuperFamily	SSF46689	1.94E-7	103	143	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	1.9E-5	107	144	IPR009057	Homeodomain-like
CDD	cd00167	1.61E-7	108	145	No hit	No description
Pfam	PF00249	3.1E-7	108	143	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	3.58E-16	351	434	IPR009057	Homeodomain-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 436 aa Download sequence Send to blast
MGRSRAAYHA GAADDLGQSK HKRKKTSNNG DSAGGVATGI NDLEKALYHC NYCNKDISGN 60 LRVKCVNCSD FDLCIECFSV GAEVHPHKSS HPYRIMDNLA FPLICADWNA DEEMLLLEGI 120 EMYGLGNWNQ VGEHVGTKNR SQIEDISKED QARRSSSSKS SGMSVGEKKP RTSDEGGVSL 180 KELSGYNFKR QEFEIEYDND AEQLLADMEF KDTDTEYERQ VKLQVLQIYS KRLDERKRRK 240 NFILDRNMLV PAPFRHDLTA EEKELCRQYR VFMRFHSKED HNNFLDSIVE HGRIVKRIQE 300 LQEARAAGCR TSAEARKYVD QKSKKGSGES ARIMKESPQS VSTGNHLQNS DQDIRAQDSW 360 DITGFLGSDL LSDAEKKLCA ERRILPIHYL DMLQTISAGI AEGNITKKAD AHELFHVDPE 420 KVDEVYELLI TRGFAQ

Sequence ? help Back to Top

Protein Sequence Length: 436 aa Download sequence Send to blast

MGRSRAAYHA GAADDLGQSK HKRKKTSNNG DSAGGVATGI NDLEKALYHC NYCNKDISGN  60
LRVKCVNCSD FDLCIECFSV GAEVHPHKSS HPYRIMDNLA FPLICADWNA DEEMLLLEGI  120
EMYGLGNWNQ VGEHVGTKNR SQIEDISKED QARRSSSSKS SGMSVGEKKP RTSDEGGVSL  180
KELSGYNFKR QEFEIEYDND AEQLLADMEF KDTDTEYERQ VKLQVLQIYS KRLDERKRRK  240
NFILDRNMLV PAPFRHDLTA EEKELCRQYR VFMRFHSKED HNNFLDSIVE HGRIVKRIQE  300
LQEARAAGCR TSAEARKYVD QKSKKGSGES ARIMKESPQS VSTGNHLQNS DQDIRAQDSW  360
DITGFLGSDL LSDAEKKLCA ERRILPIHYL DMLQTISAGI AEGNITKKAD AHELFHVDPE  420
KVDEVYELLI TRGFAQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6cw2_C	7e-28	48	145	5	102	Transcriptional adapter 2
6cw3_E	8e-28	48	145	5	102	Transcriptional adapter 2
6cw3_G	8e-28	48	145	5	102	Transcriptional adapter 2
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Functional Description ? help Back to Top
Source	Description
UniProt	Required for the function of some acidic activation domains, which activate transcription from a distant site. The exact mechanism of action is not yet known (By similarity). ADA2 stimulates the acetyltransferase activity of GCN5 on free histones or nucleosomes, probably by opening up the promoter region. Mediates auxin and cytokinin signals in the control of cell proliferation and might be involved in repression of a freezing tolerance pathway at warm temperature (PubMed:12615937, PubMed:12747832). Involved in the positive regulation of salt-induced gene expression by maintaining locus-specific acetylation of histones H4 and H3 (PubMed:21193996). {ECO:0000250, ECO:0000269\|PubMed:12615937, ECO:0000269\|PubMed:12747832, ECO:0000269\|PubMed:21193996}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	678456708

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027064377.1	1e-180	transcriptional adapter ADA2-like isoform X1
Refseq	XP_027170025.1	1e-180	transcriptional adapter ADA2-like
Swissprot	Q9ATB4	1e-142	TAD2B_ARATH; Transcriptional adapter ADA2b
TrEMBL	A0A068V9T7	1e-179	A0A068V9T7_COFCA; Transcriptional adapter
STRING	EMJ16449	1e-171	(Prunus persica)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2447	12	15

Publications ? help Back to Top
Vlachonasios KE,Thomashow MF,Triezenberg SJ Disruption mutations of ADA2b and GCN5 transcriptional adaptor genes dramatically affect Arabidopsis growth, development, and gene expression. Plant Cell, 2003. 15(3): p. 626-38 [PMID:12615937] Sieberer T,Hauser MT,Seifert GJ,Luschnig C PROPORZ1, a putative Arabidopsis transcriptional adaptor protein, mediates auxin and cytokinin signals in the control of cell proliferation. Curr. Biol., 2003. 13(10): p. 837-42 [PMID:12747832] Kerschen A,Napoli CA,Jorgensen RA,Müller AE Effectiveness of RNA interference in transgenic plants. FEBS Lett., 2004. 566(1-3): p. 223-8 [PMID:15147899] Hark AT, et al. Two Arabidopsis orthologs of the transcriptional coactivator ADA2 have distinct biological functions. Biochim. Biophys. Acta, 2009. 1789(2): p. 117-24 [PMID:18929690] Anzola JM, et al. Putative Arabidopsis transcriptional adaptor protein (PROPORZ1) is required to modulate histone acetylation in response to auxin. Proc. Natl. Acad. Sci. U.S.A., 2010. 107(22): p. 10308-13 [PMID:20479223] Kaldis A,Tsementzi D,Tanriverdi O,Vlachonasios KE Arabidopsis thaliana transcriptional co-activators ADA2b and SGF29a are implicated in salt stress responses. Planta, 2011. 233(4): p. 749-62 [PMID:21193996] Vlachonasios KE,Kaldis A,Nikoloudi A,Tsementzi D The role of transcriptional coactivator ADA2b in Arabidopsis abiotic stress responses. Plant Signal Behav, 2011. 6(10): p. 1475-8 [PMID:21897124] Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Kazama D,Kurusu T,Mitsuda N,Ohme-Takagi M,Tada Y Involvement of elevated proline accumulation in enhanced osmotic stress tolerance in Arabidopsis conferred by chimeric repressor gene silencing technology. Plant Signal Behav, 2014. 9(3): p. e28211 [PMID:24614501] Kim JY,Oh JE,Noh YS,Noh B Epigenetic control of juvenile-to-adult phase transition by the Arabidopsis SAGA-like complex. Plant J., 2015. 83(3): p. 537-45 [PMID:26095998] Kazama D, et al. Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis. Plants (Basel), 2013. 2(4): p. 769-85 [PMID:27137403] Simon MK,Skinner DJ,Gallagher TL,Gasser CS Integument Development in Arabidopsis Depends on Interaction of YABBY Protein INNER NO OUTER with Coactivators and Corepressors. Genetics, 2017. 207(4): p. 1489-1500 [PMID:28971961] Lai J, et al. The Transcriptional Coactivator ADA2b Recruits a Structural Maintenance Protein to Double-Strand Breaks during DNA Repair in Plants. Plant Physiol., 2018. 176(4): p. 2613-2622 [PMID:29463775] Kotak J, et al. The histone acetyltransferase GCN5 and the transcriptional coactivator ADA2b affect leaf development and trichome morphogenesis in Arabidopsis. Planta, 2018. 248(3): p. 613-628 [PMID:29846775]