PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | 28324.m000396 | ||||||||
Common Name | RCOM_0225530 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae; Ricinus
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Family | E2F/DP | ||||||||
Protein Properties | Length: 451aa MW: 49917 Da PI: 5.4221 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.6 | 1.9e-27 | 155 | 220 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg 28324.m000396 155 RYDSSLGLLTKKFVNLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 220 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 2.1E-29 | 152 | 222 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.1E-34 | 155 | 220 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 8.43E-17 | 155 | 218 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.9E-24 | 157 | 220 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 5.62E-48 | 234 | 337 | No hit | No description |
SuperFamily | SSF144074 | 1.12E-33 | 234 | 337 | No hit | No description |
Pfam | PF16421 | 2.4E-33 | 236 | 335 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 451 aa Download sequence Send to blast |
MSGSARASTR PPPTAAAAAA SASTPTPAPA GPILPPLRRH LAFATMKPPF VPPDDYHRFT 60 PSSSTNNRAA DREAEGIVLR SPTLKRKNGM DENGFESSSA FCGDVSNSPF RTPVSAKGGR 120 TYSKSKASKG NRSGPQTLVP NIDSPSPLTP AGSCRYDSSL GLLTKKFVNL IKHAEDGILD 180 LNKAAETLEV QKRRIYDITN VLEGIGLIEK KLKNRIRWKG VDTSRPGEPD GDASLLQAEI 240 EKLSMEERRL DDQTREMQER LRELIEDENN QKWLFVTEED IKSLPCFQNQ TLIAVKAPHG 300 TTLEVPDPDE AVDYPQRRYR IILRSSMGPI DVYLVSQFEE NFEEANGEPS TSFPHASSSC 360 SNEIPKKQVI NEQKIQKRVE PQMQQNDADY WLLSDADVSI TDMWRTDANV EWNDVNMLRA 420 DFGIPDVQTP RAQTPPSGMA EVPTGVNSTL R |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 3e-25 | 150 | 221 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00293 | DAP | Transfer from AT2G36010 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | 28324.m000396 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_025015055.1 | 0.0 | LOW QUALITY PROTEIN: transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-165 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | B9SVY5 | 0.0 | B9SVY5_RICCO; E2F4,5, putative | ||||
STRING | XP_002530154.1 | 0.0 | (Ricinus communis) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF1947 | 34 | 90 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-165 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | 28324.m000396 |
Publications ? help Back to Top | |||
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