PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Salvia splendens
WOX Family
Species TF ID Description
TEY19035.1WOX family protein
TEY19352.1WOX family protein
TEY20170.1WOX family protein
TEY22685.1WOX family protein
TEY24392.1WOX family protein
TEY27009.1WOX family protein
TEY27051.1WOX family protein
TEY31341.1WOX family protein
TEY33932.1WOX family protein
TEY34442.1WOX family protein
TEY37369.1WOX family protein
TEY38531.1WOX family protein
TEY40289.1WOX family protein
TEY42216.1WOX family protein
TEY43324.1WOX family protein
TEY44575.1WOX family protein
TEY46450.1WOX family protein
TEY48568.1WOX family protein
TEY53982.1WOX family protein
TEY57347.1WOX family protein
TEY60083.1WOX family protein
TEY60470.1WOX family protein
TEY64198.1WOX family protein
TEY67566.1WOX family protein
TEY68875.1WOX family protein
TEY75262.1WOX family protein
TEY77923.1WOX family protein
TEY84573.1WOX family protein
TEY87710.1WOX family protein
TEY88708.1WOX family protein
TEY89888.1WOX family protein
TEY93092.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590