PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Salvia splendens
EIL Family
Species TF ID Description
TEY11610.1EIL family protein
TEY13005.1EIL family protein
TEY14760.1EIL family protein
TEY17189.1EIL family protein
TEY17258.1EIL family protein
TEY20060.1EIL family protein
TEY22750.1EIL family protein
TEY32438.1EIL family protein
TEY41251.1EIL family protein
TEY57289.1EIL family protein
TEY58109.1EIL family protein
TEY60122.1EIL family protein
TEY63982.1EIL family protein
TEY70498.1EIL family protein
TEY72540.1EIL family protein
TEY78977.1EIL family protein
TEY81436.1EIL family protein
TEY86202.1EIL family protein
TEY88751.1EIL family protein
TEY90236.1EIL family protein
TEY91711.1EIL family protein
EIL Family Introduction

The gaseous phytohormone ethylene regulates various processes related to growth, development, and stress response of higher plants. A largely linear pathway of ethylene signaling was revealed by a number of molecular genetic studies. In the pathway, Ethylene-insensitive3 (EIN3) and EIN3-like (EIL) proteins are the key transcription factors. The EIN3/EIL proteins were shown to regulate expression of the GCC-box-binding transcription factors, ethylene-response factors. It is known that the phenotype of the Arabidopsis thaliana EIN3 (AtEIN3)-deficient mutants, e.g. long seedlings in the presence of ethylene or its precursor, is suppressed by overexpression of Arabidopsis EIL1 (AtEIL1) or EIL2 (AtEIL2), indicating the functional equivalence of these proteins.

In the present study, a region corresponding to the major DBD of the EIN3/EIL transcription factor family, which is the key factor in the ethylene signaling, was identified. The isolated domain exists in a monomeric form and retained the sequence specificity for the DNA binding. The structure determined by NMR spectroscopy consists of five alpha-helices, packing into a novel fold dissimilar to known DBDs. An NMR titration analysis suggested that a region including the key mutation site, ein3-3 site, was shown to be involved in DNA binding.

Yamasaki K, Kigawa T, Inoue M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Tomo Y, Terada T, Shirouzu M, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3.
J Mol Biol, 2005. 348(2): p. 253-64.
PMID: 15811366