PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Quercus suber
WOX Family
Species TF ID Description
XP_023873399.1WOX family protein
XP_023874797.1WOX family protein
XP_023876315.1WOX family protein
XP_023876316.1WOX family protein
XP_023880720.1WOX family protein
XP_023880721.1WOX family protein
XP_023880722.1WOX family protein
XP_023880961.1WOX family protein
XP_023888243.1WOX family protein
XP_023893569.1WOX family protein
XP_023897031.1WOX family protein
XP_023905918.1WOX family protein
XP_023908230.1WOX family protein
XP_023908458.1WOX family protein
XP_023908459.1WOX family protein
XP_023913899.1WOX family protein
XP_023927834.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590