PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Prunus avium
HD-ZIP Family
Species TF ID Description
Pav_co4010635.1_g010.1.mkHD-ZIP family protein
Pav_co4029521.1_g010.1.mkHD-ZIP family protein
Pav_sc0000009.1_g670.1.mkHD-ZIP family protein
Pav_sc0000094.1_g040.1.mkHD-ZIP family protein
Pav_sc0000103.1_g1450.1.mkHD-ZIP family protein
Pav_sc0000138.1_g870.1.mkHD-ZIP family protein
Pav_sc0000220.1_g1760.1.mkHD-ZIP family protein
Pav_sc0000220.1_g2770.1.mkHD-ZIP family protein
Pav_sc0000257.1_g230.1.mkHD-ZIP family protein
Pav_sc0000259.1_g300.1.mkHD-ZIP family protein
Pav_sc0000305.1_g100.1.mkHD-ZIP family protein
Pav_sc0000348.1_g1180.1.mkHD-ZIP family protein
Pav_sc0000395.1_g240.1.mkHD-ZIP family protein
Pav_sc0000481.1_g080.1.mkHD-ZIP family protein
Pav_sc0000586.1_g780.1.mkHD-ZIP family protein
Pav_sc0000624.1_g060.1.mkHD-ZIP family protein
Pav_sc0000624.1_g070.1.mkHD-ZIP family protein
Pav_sc0000675.1_g1210.1.mkHD-ZIP family protein
Pav_sc0000759.1_g380.1.mkHD-ZIP family protein
Pav_sc0000766.1_g310.1.mkHD-ZIP family protein
Pav_sc0000800.1_g680.1.mkHD-ZIP family protein
Pav_sc0000978.1_g030.1.mkHD-ZIP family protein
Pav_sc0001124.1_g280.1.mkHD-ZIP family protein
Pav_sc0001181.1_g1190.1.mkHD-ZIP family protein
Pav_sc0001263.1_g110.1.mkHD-ZIP family protein
Pav_sc0001405.1_g720.1.mkHD-ZIP family protein
Pav_sc0001710.1_g870.1.mkHD-ZIP family protein
Pav_sc0001718.1_g270.1.mkHD-ZIP family protein
Pav_sc0002118.1_g060.1.mkHD-ZIP family protein
Pav_sc0003492.1_g200.1.mkHD-ZIP family protein
Pav_sc0004416.1_g110.1.brHD-ZIP family protein
Pav_sc0007634.1_g010.1.mkHD-ZIP family protein
Pav_sc0010169.1_g050.1.brHD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401