PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Mucuna pruriens
ARF Family
Species TF ID Description
RDX63760.1ARF family protein
RDX65149.1ARF family protein
RDX65414.1ARF family protein
RDX66920.1ARF family protein
RDX67368.1ARF family protein
RDX68914.1ARF family protein
RDX71002.1ARF family protein
RDX71938.1ARF family protein
RDX73352.1ARF family protein
RDX74515.1ARF family protein
RDX75107.1ARF family protein
RDX77688.1ARF family protein
RDX78217.1ARF family protein
RDX80746.1ARF family protein
RDX81840.1ARF family protein
RDX83025.1ARF family protein
RDX85638.1ARF family protein
RDX87105.1ARF family protein
RDX90064.1ARF family protein
RDX94285.1ARF family protein
RDX96947.1ARF family protein
RDX99358.1ARF family protein
RDY03411.1ARF family protein
RDY04517.1ARF family protein
RDY05326.1ARF family protein
RDY05473.1ARF family protein
RDY07538.1ARF family protein
RDY09545.1ARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969