PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Macleaya cordata
WRKY Family
Species TF ID Description
OVA00086.1WRKY family protein
OVA00985.1WRKY family protein
OVA01933.1WRKY family protein
OVA02114.1WRKY family protein
OVA02525.1WRKY family protein
OVA03194.1WRKY family protein
OVA03405.1WRKY family protein
OVA03995.1WRKY family protein
OVA04145.1WRKY family protein
OVA05322.1WRKY family protein
OVA06930.1WRKY family protein
OVA07904.1WRKY family protein
OVA08634.1WRKY family protein
OVA08821.1WRKY family protein
OVA09233.1WRKY family protein
OVA09234.1WRKY family protein
OVA09580.1WRKY family protein
OVA09775.1WRKY family protein
OVA09944.1WRKY family protein
OVA10618.1WRKY family protein
OVA11299.1WRKY family protein
OVA11324.1WRKY family protein
OVA11453.1WRKY family protein
OVA12691.1WRKY family protein
OVA13043.1WRKY family protein
OVA13308.1WRKY family protein
OVA13402.1WRKY family protein
OVA13472.1WRKY family protein
OVA13512.1WRKY family protein
OVA13588.1WRKY family protein
OVA13711.1WRKY family protein
OVA15112.1WRKY family protein
OVA15113.1WRKY family protein
OVA15888.1WRKY family protein
OVA16621.1WRKY family protein
OVA16746.1WRKY family protein
OVA16849.1WRKY family protein
OVA16948.1WRKY family protein
OVA17023.1WRKY family protein
OVA17217.1WRKY family protein
OVA17303.1WRKY family protein
OVA17467.1WRKY family protein
OVA17832.1WRKY family protein
OVA18208.1WRKY family protein
OVA19096.1WRKY family protein
OVA20420.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701