PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Momordica charantia
WRKY Family
Species TF ID Description
XP_022131434.1WRKY family protein
XP_022131459.1WRKY family protein
XP_022131756.1WRKY family protein
XP_022132094.1WRKY family protein
XP_022132496.1WRKY family protein
XP_022133061.1WRKY family protein
XP_022133095.1WRKY family protein
XP_022134163.1WRKY family protein
XP_022134164.1WRKY family protein
XP_022134623.1WRKY family protein
XP_022134891.1WRKY family protein
XP_022135102.1WRKY family protein
XP_022135705.1WRKY family protein
XP_022136030.1WRKY family protein
XP_022136032.1WRKY family protein
XP_022136033.1WRKY family protein
XP_022136034.1WRKY family protein
XP_022136601.1WRKY family protein
XP_022136661.1WRKY family protein
XP_022136815.1WRKY family protein
XP_022137828.1WRKY family protein
XP_022139903.1WRKY family protein
XP_022140213.1WRKY family protein
XP_022140883.1WRKY family protein
XP_022140884.1WRKY family protein
XP_022140885.1WRKY family protein
XP_022141783.1WRKY family protein
XP_022142052.1WRKY family protein
XP_022142261.1WRKY family protein
XP_022142684.1WRKY family protein
XP_022143026.1WRKY family protein
XP_022143033.1WRKY family protein
XP_022143503.1WRKY family protein
XP_022143903.1WRKY family protein
XP_022145186.1WRKY family protein
XP_022145625.1WRKY family protein
XP_022145626.1WRKY family protein
XP_022146052.1WRKY family protein
XP_022146650.1WRKY family protein
XP_022146751.1WRKY family protein
XP_022146859.1WRKY family protein
XP_022147246.1WRKY family protein
XP_022147294.1WRKY family protein
XP_022147296.1WRKY family protein
XP_022147889.1WRKY family protein
XP_022147890.1WRKY family protein
XP_022147986.1WRKY family protein
XP_022148532.1WRKY family protein
XP_022149157.1WRKY family protein
XP_022149623.1WRKY family protein
XP_022149678.1WRKY family protein
XP_022149969.1WRKY family protein
XP_022151088.1WRKY family protein
XP_022151251.1WRKY family protein
XP_022151361.1WRKY family protein
XP_022151370.1WRKY family protein
XP_022153408.1WRKY family protein
XP_022154146.1WRKY family protein
XP_022154851.1WRKY family protein
XP_022154985.1WRKY family protein
XP_022155264.1WRKY family protein
XP_022155836.1WRKY family protein
XP_022156527.1WRKY family protein
XP_022157003.1WRKY family protein
XP_022157004.1WRKY family protein
XP_022157265.1WRKY family protein
XP_022157297.1WRKY family protein
XP_022157612.1WRKY family protein
XP_022157717.1WRKY family protein
XP_022159094.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701