PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Momordica charantia
AP2 Family
Species TF ID Description
XP_022131292.1AP2 family protein
XP_022131293.1AP2 family protein
XP_022133074.1AP2 family protein
XP_022133076.1AP2 family protein
XP_022133310.1AP2 family protein
XP_022135382.1AP2 family protein
XP_022135436.1AP2 family protein
XP_022136672.1AP2 family protein
XP_022136720.1AP2 family protein
XP_022138967.1AP2 family protein
XP_022143709.1AP2 family protein
XP_022144462.1AP2 family protein
XP_022145541.1AP2 family protein
XP_022146223.1AP2 family protein
XP_022146224.1AP2 family protein
XP_022149499.1AP2 family protein
XP_022149500.1AP2 family protein
XP_022150644.1AP2 family protein
XP_022151327.1AP2 family protein
XP_022152161.1AP2 family protein
XP_022153451.1AP2 family protein
XP_022153496.1AP2 family protein
XP_022153506.1AP2 family protein
XP_022153515.1AP2 family protein
XP_022153520.1AP2 family protein
XP_022156831.1AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444

Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102