PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Lupinus angustifolius
AP2 Family
Species TF ID Description
OIV89004AP2 family protein
OIV89342AP2 family protein
OIV93031AP2 family protein
OIV93866AP2 family protein
OIV94481AP2 family protein
OIV94730AP2 family protein
OIV97679AP2 family protein
OIV99086AP2 family protein
OIV99418AP2 family protein
OIW03080AP2 family protein
OIW03424AP2 family protein
OIW03728AP2 family protein
OIW03945AP2 family protein
OIW04029AP2 family protein
OIW04916AP2 family protein
OIW05726AP2 family protein
OIW05781AP2 family protein
OIW06152AP2 family protein
OIW07192AP2 family protein
OIW08148AP2 family protein
OIW09160AP2 family protein
OIW10948AP2 family protein
OIW11209AP2 family protein
OIW11210AP2 family protein
OIW11471AP2 family protein
OIW11800AP2 family protein
OIW13252AP2 family protein
OIW13776AP2 family protein
OIW14922AP2 family protein
OIW15558AP2 family protein
OIW17093AP2 family protein
OIW18684AP2 family protein
OIW19421AP2 family protein
OIW19852AP2 family protein
OIW21774AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102