PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Herrania umbratica
WRKY Family
Species TF ID Description
XP_021273623.1WRKY family protein
XP_021273672.1WRKY family protein
XP_021274079.1WRKY family protein
XP_021274893.1WRKY family protein
XP_021276025.1WRKY family protein
XP_021276785.1WRKY family protein
XP_021277197.1WRKY family protein
XP_021277198.1WRKY family protein
XP_021277715.1WRKY family protein
XP_021277727.1WRKY family protein
XP_021278172.1WRKY family protein
XP_021279389.1WRKY family protein
XP_021279390.1WRKY family protein
XP_021279662.1WRKY family protein
XP_021279718.1WRKY family protein
XP_021279743.1WRKY family protein
XP_021280339.1WRKY family protein
XP_021280645.1WRKY family protein
XP_021281139.1WRKY family protein
XP_021281140.1WRKY family protein
XP_021281141.1WRKY family protein
XP_021281444.1WRKY family protein
XP_021281745.1WRKY family protein
XP_021282074.1WRKY family protein
XP_021282075.1WRKY family protein
XP_021284009.1WRKY family protein
XP_021284777.1WRKY family protein
XP_021284786.1WRKY family protein
XP_021285068.1WRKY family protein
XP_021285081.1WRKY family protein
XP_021286059.1WRKY family protein
XP_021286255.1WRKY family protein
XP_021286359.1WRKY family protein
XP_021286360.1WRKY family protein
XP_021286562.1WRKY family protein
XP_021286563.1WRKY family protein
XP_021287397.1WRKY family protein
XP_021287555.1WRKY family protein
XP_021287556.1WRKY family protein
XP_021287557.1WRKY family protein
XP_021287648.1WRKY family protein
XP_021287649.1WRKY family protein
XP_021289025.1WRKY family protein
XP_021289195.1WRKY family protein
XP_021289196.1WRKY family protein
XP_021289978.1WRKY family protein
XP_021290063.1WRKY family protein
XP_021290505.1WRKY family protein
XP_021290890.1WRKY family protein
XP_021291030.1WRKY family protein
XP_021293950.1WRKY family protein
XP_021294286.1WRKY family protein
XP_021294288.1WRKY family protein
XP_021294776.1WRKY family protein
XP_021295250.1WRKY family protein
XP_021295251.1WRKY family protein
XP_021297071.1WRKY family protein
XP_021297186.1WRKY family protein
XP_021297187.1WRKY family protein
XP_021297553.1WRKY family protein
XP_021297669.1WRKY family protein
XP_021298235.1WRKY family protein
XP_021298442.1WRKY family protein
XP_021299079.1WRKY family protein
XP_021299602.1WRKY family protein
XP_021299604.1WRKY family protein
XP_021299606.1WRKY family protein
XP_021299838.1WRKY family protein
XP_021299839.1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701