PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Hevea brasiliensis
SBP Family
Species TF ID Description
XP_021635047.1SBP family protein
XP_021635647.1SBP family protein
XP_021635648.1SBP family protein
XP_021635649.1SBP family protein
XP_021635650.1SBP family protein
XP_021635651.1SBP family protein
XP_021635652.1SBP family protein
XP_021635653.1SBP family protein
XP_021636923.1SBP family protein
XP_021636924.1SBP family protein
XP_021640197.1SBP family protein
XP_021642281.1SBP family protein
XP_021642486.1SBP family protein
XP_021642487.1SBP family protein
XP_021642488.1SBP family protein
XP_021644278.1SBP family protein
XP_021644339.1SBP family protein
XP_021644340.1SBP family protein
XP_021644341.1SBP family protein
XP_021652561.1SBP family protein
XP_021652562.1SBP family protein
XP_021658403.1SBP family protein
XP_021663003.1SBP family protein
XP_021663004.1SBP family protein
XP_021663005.1SBP family protein
XP_021663006.1SBP family protein
XP_021663007.1SBP family protein
XP_021663008.1SBP family protein
XP_021663009.1SBP family protein
XP_021663010.1SBP family protein
XP_021664713.1SBP family protein
XP_021664715.1SBP family protein
XP_021664716.1SBP family protein
XP_021665390.1SBP family protein
XP_021665391.1SBP family protein
XP_021665392.1SBP family protein
XP_021665393.1SBP family protein
XP_021667340.1SBP family protein
XP_021667341.1SBP family protein
XP_021668748.1SBP family protein
XP_021668750.1SBP family protein
XP_021668751.1SBP family protein
XP_021668752.1SBP family protein
XP_021674880.1SBP family protein
XP_021674882.1SBP family protein
XP_021674883.1SBP family protein
XP_021676155.1SBP family protein
XP_021676156.1SBP family protein
XP_021676158.1SBP family protein
XP_021676159.1SBP family protein
XP_021677940.1SBP family protein
XP_021677941.1SBP family protein
XP_021677942.1SBP family protein
XP_021681200.1SBP family protein
XP_021682433.1SBP family protein
XP_021683313.1SBP family protein
XP_021683314.1SBP family protein
XP_021683364.1SBP family protein
XP_021686538.1SBP family protein
XP_021688870.1SBP family protein
XP_021688871.1SBP family protein
XP_021688872.1SBP family protein
XP_021688873.1SBP family protein
XP_021688874.1SBP family protein
XP_021688875.1SBP family protein
XP_021688876.1SBP family protein
SBP Family Introduction

SQUAMOSA promoter binding proteins (SBPs) form a major family of plant-specific transcription factors related to flower development. Although SBPs are heterogeneous in primary structure, they share a highly conserved DNA-binding domain (DBD) that has been suggested to be zinc binding. Here we report the NMR solution structures of DBDs of two SBPs of Arabidopsis thaliana, SPL4 and SPL7. The two share essentially the same structural features. Each structure contains two zinc-binding sites consisting of eight Cys or His residues in a Cys3HisCys2HisCys or Cys6HisCys sequence motif in which the first four residues coordinate to one zinc and the last four coordinate to the other. These structures are dissimilar to other known zinc-binding structures, and thus represent a novel type of zinc-binding motif. The electrostatic profile on the surface suggested that a continuous region, including all the conserved basic residues, is involved in the DNA binding, the mode of which is likely to be novel as well.

Yamasaki K, Kigawa T, Inoue M, Tateno M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Nunokawa E, Ishizuka Y, Terada T, Shirouzu M, Osanai T, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
A novel zinc-binding motif revealed by solution structures of DNA-binding domains of Arabidopsis SBP-family transcription factors
J Mol Biol. 2004 Mar 12;337(1):49-63.
PMID: 15001351

SBP-box genes were first characterized as SQUAMOSA promoter binding proteins (SBPs) to regulate the expression of MADS-box genes in early flower development of A. majus (Klein et al., 1996). Since then, SBP-box genes have been identified in many plants including green alga, moss, silver birch, A. majus, Arabidopsis and maize. They play critical roles in regulating flower and fruit development as well as other physiological processes ([Moreno et al., 1997],[Eriksson et al., 2004], [Lannenpaa et al., 2004], [Arazi et al., 2005] and [Kropat et al., 2005]). It has been reported that Arabidopsis SPL3, SPL8 and SPL14 involves in flowering, sporogenesis, GA signaling and toxin resistance ([Cardon et al., 1997], [Unte et al., 2003], [Stone et al., 2005] and [Zhang et al., 2006]) while maize tga1 and tomato LeSPL-CNR affect fruit development ([Wang et al., 2005a] and [Manning et al., 2006]).

SBP-box genes encode proteins sharing a conserved DNA-binding domain of 79 amino acid residues. It has been proved that the DNA-binding domain of SBP-box genes is necessary and sufficient to bind to a palindromic GTAC core motif ([Klein et al., 1996], [Cardon et al., 1997], [Cardon et al., 1999], [Lannenpaa et al., 2004] and [Birkenbihl et al., 2005]). Studies on the NMR solution structure of the fragment of Arabidopsis SPL4 and SPL7 revealed that the DNA-binding domain of SBPs consisted of two separate zinc-binding sites. One zinc finger is C3H or C4 and the other is C2HC (Yamasaki et al., 2004 K. Yamasaki et al.,).

Guo AY, Zhu QH, Gu X, Ge S, Yang J, Luo J.
Genome-wide identification and evolutionary analysis of the plant specific SBP-box transcription factor family.
Gene. 2008 Jul 15;418(1-2):1-8.
PMID: 18495384