PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Hevea brasiliensis
HSF Family
Species TF ID Description
XP_021636397.1HSF family protein
XP_021636783.1HSF family protein
XP_021637256.1HSF family protein
XP_021640001.1HSF family protein
XP_021643077.1HSF family protein
XP_021643078.1HSF family protein
XP_021644844.1HSF family protein
XP_021646043.1HSF family protein
XP_021646672.1HSF family protein
XP_021648609.1HSF family protein
XP_021648822.1HSF family protein
XP_021648823.1HSF family protein
XP_021648824.1HSF family protein
XP_021648826.1HSF family protein
XP_021648827.1HSF family protein
XP_021650099.1HSF family protein
XP_021650172.1HSF family protein
XP_021650815.1HSF family protein
XP_021651772.1HSF family protein
XP_021656118.1HSF family protein
XP_021657775.1HSF family protein
XP_021657776.1HSF family protein
XP_021659679.1HSF family protein
XP_021659685.1HSF family protein
XP_021659694.1HSF family protein
XP_021659701.1HSF family protein
XP_021659709.1HSF family protein
XP_021664402.1HSF family protein
XP_021664512.1HSF family protein
XP_021667256.1HSF family protein
XP_021668475.1HSF family protein
XP_021668476.1HSF family protein
XP_021669691.1HSF family protein
XP_021669692.1HSF family protein
XP_021676457.1HSF family protein
XP_021676458.1HSF family protein
XP_021676459.1HSF family protein
XP_021676460.1HSF family protein
XP_021676972.1HSF family protein
XP_021678492.1HSF family protein
XP_021678507.1HSF family protein
XP_021678800.1HSF family protein
XP_021678801.1HSF family protein
XP_021678802.1HSF family protein
XP_021682999.1HSF family protein
XP_021683000.1HSF family protein
XP_021687474.1HSF family protein
XP_021689590.1HSF family protein
XP_021689893.1HSF family protein
XP_021690564.1HSF family protein
HSF Family Introduction

Heat stress transcription factors (Hsfs) are the major regulators of the plant heat stress (hs) response. Sequencing of the Arabidopsis genome revealed the existence of 21 open-reading frames (ORFs) encoding putative Hsfs assigned to classes A-C. Here we present results of a functional genomics approach to the Arabidopsis Hsf family focused on the analysis of their C-terminal domains (CTDs) harboring conserved modules for their function as transcription factors and their intracellular localization. Using reporter assays in tobacco protoplasts and yeast as well as glutathione-S-transferase (GST) pull-down assays, we demonstrate that short peptide motifs enriched with aromatic and large hydrophobic amino acid (aa) residues embedded in an acidic surrounding (AHA motifs) are essential for transcriptional activity of class A Hsfs. In contrast to this, class B and C Hsfs lack AHA motifs and have no activator function on their own. We also provide evidence for the function of a leucine (Leu)-rich region centered around a conserved QMGΦL motif at the very C-terminus as a nuclear export signal (NES) of class A Hsfs. Sequence comparison indicates that the combination of a C-terminal AHA motif with the consensus sequence FWxxF/L,F/I/L as well as the adjacent NES represents a signature domain for plant class A Hsfs, which allowed to identify more than 60 new Hsfs from the expressed sequence tag (EST) database.

Kotak S, Port M, Ganguli A, Bicker F, von Koskull-Doring P.
Characterization of C-terminal domains of Arabidopsis heat stress transcription factors (Hsfs) and identification of a new signature combination of plant class A Hsfs with AHA and NES motifs essential for activator function and intracellular localization.
Plant J, 2004. 39(1): p. 98-112.
PMID: 15200645