PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Durio zibethinus
FAR1 Family
Species TF ID Description
XP_022714799.1FAR1 family protein
XP_022716242.1FAR1 family protein
XP_022716243.1FAR1 family protein
XP_022716554.1FAR1 family protein
XP_022719843.1FAR1 family protein
XP_022719845.1FAR1 family protein
XP_022719846.1FAR1 family protein
XP_022722430.1FAR1 family protein
XP_022722431.1FAR1 family protein
XP_022722777.1FAR1 family protein
XP_022722778.1FAR1 family protein
XP_022722779.1FAR1 family protein
XP_022722780.1FAR1 family protein
XP_022722974.1FAR1 family protein
XP_022722975.1FAR1 family protein
XP_022723019.1FAR1 family protein
XP_022723078.1FAR1 family protein
XP_022723855.1FAR1 family protein
XP_022726330.1FAR1 family protein
XP_022727897.1FAR1 family protein
XP_022728322.1FAR1 family protein
XP_022728323.1FAR1 family protein
XP_022728324.1FAR1 family protein
XP_022729454.1FAR1 family protein
XP_022729455.1FAR1 family protein
XP_022730590.1FAR1 family protein
XP_022730591.1FAR1 family protein
XP_022730592.1FAR1 family protein
XP_022730593.1FAR1 family protein
XP_022731195.1FAR1 family protein
XP_022734205.1FAR1 family protein
XP_022734921.1FAR1 family protein
XP_022734922.1FAR1 family protein
XP_022734923.1FAR1 family protein
XP_022734924.1FAR1 family protein
XP_022734925.1FAR1 family protein
XP_022734926.1FAR1 family protein
XP_022735012.1FAR1 family protein
XP_022735013.1FAR1 family protein
XP_022735014.1FAR1 family protein
XP_022735180.1FAR1 family protein
XP_022735181.1FAR1 family protein
XP_022735182.1FAR1 family protein
XP_022735183.1FAR1 family protein
XP_022738509.1FAR1 family protein
XP_022738632.1FAR1 family protein
XP_022738633.1FAR1 family protein
XP_022739360.1FAR1 family protein
XP_022739362.1FAR1 family protein
XP_022739363.1FAR1 family protein
XP_022743905.1FAR1 family protein
XP_022750496.1FAR1 family protein
XP_022752474.1FAR1 family protein
XP_022752818.1FAR1 family protein
XP_022752819.1FAR1 family protein
XP_022753561.1FAR1 family protein
XP_022753562.1FAR1 family protein
XP_022753564.1FAR1 family protein
XP_022754126.1FAR1 family protein
XP_022754127.1FAR1 family protein
XP_022758796.1FAR1 family protein
XP_022758797.1FAR1 family protein
XP_022758798.1FAR1 family protein
XP_022758799.1FAR1 family protein
XP_022758800.1FAR1 family protein
XP_022758801.1FAR1 family protein
XP_022758802.1FAR1 family protein
XP_022760423.1FAR1 family protein
XP_022760424.1FAR1 family protein
XP_022760638.1FAR1 family protein
XP_022760639.1FAR1 family protein
XP_022760640.1FAR1 family protein
XP_022761649.1FAR1 family protein
XP_022761664.1FAR1 family protein
XP_022761665.1FAR1 family protein
XP_022762616.1FAR1 family protein
XP_022762618.1FAR1 family protein
XP_022763839.1FAR1 family protein
XP_022764330.1FAR1 family protein
XP_022764332.1FAR1 family protein
XP_022765671.1FAR1 family protein
XP_022765672.1FAR1 family protein
XP_022765673.1FAR1 family protein
XP_022765674.1FAR1 family protein
XP_022769924.1FAR1 family protein
XP_022771564.1FAR1 family protein
XP_022771565.1FAR1 family protein
XP_022771566.1FAR1 family protein
XP_022771568.1FAR1 family protein
XP_022772524.1FAR1 family protein
XP_022772525.1FAR1 family protein
XP_022774549.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885