PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Chromochloris zofingiensis
bZIP Family
Species TF ID Description
Cz02g23080.t1bZIP family protein
Cz02g24190.t1bZIP family protein
Cz02g41160.t1bZIP family protein
Cz04g21220.t1bZIP family protein
Cz05g04290.t1bZIP family protein
Cz05g36050.t1bZIP family protein
Cz06g11180.t1bZIP family protein
Cz06g16030.t1bZIP family protein
Cz08g07250.t1bZIP family protein
Cz09g18200.t1bZIP family protein
Cz10g02030.t1bZIP family protein
Cz10g24190.t1bZIP family protein
Cz10g29130.t1bZIP family protein
Cz11g01210.t1bZIP family protein
Cz13g00180.t1bZIP family protein
Cz14g04180.t1bZIP family protein
Cz15g08220.t1bZIP family protein
Cz15g19130.t1bZIP family protein
Cz15g21170.t1bZIP family protein
Cz17g03110.t1bZIP family protein
Cz17g07180.t1bZIP family protein
UNPLg00449.t1bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833