PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Cucurbita moschata
NF-YA Family
Species TF ID Description
XP_022925987.1NF-YA family protein
XP_022925988.1NF-YA family protein
XP_022926733.1NF-YA family protein
XP_022926734.1NF-YA family protein
XP_022926735.1NF-YA family protein
XP_022926860.1NF-YA family protein
XP_022926867.1NF-YA family protein
XP_022928596.1NF-YA family protein
XP_022934917.1NF-YA family protein
XP_022938084.1NF-YA family protein
XP_022938086.1NF-YA family protein
XP_022938087.1NF-YA family protein
XP_022938088.1NF-YA family protein
XP_022944164.1NF-YA family protein
XP_022944165.1NF-YA family protein
XP_022944166.1NF-YA family protein
XP_022944167.1NF-YA family protein
XP_022944169.1NF-YA family protein
XP_022946727.1NF-YA family protein
XP_022946728.1NF-YA family protein
XP_022946729.1NF-YA family protein
XP_022946730.1NF-YA family protein
XP_022953565.1NF-YA family protein
XP_022953566.1NF-YA family protein
XP_022953567.1NF-YA family protein
XP_022956068.1NF-YA family protein
XP_022958505.1NF-YA family protein
XP_022958506.1NF-YA family protein
XP_022960498.1NF-YA family protein
XP_022960499.1NF-YA family protein
XP_022960500.1NF-YA family protein
XP_022960501.1NF-YA family protein
XP_022961152.1NF-YA family protein
XP_022961153.1NF-YA family protein
XP_022961154.1NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982