PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Cynara cardunculus var. scolymus
FAR1 Family
Species TF ID Description
XP_024958877.1FAR1 family protein
XP_024958896.1FAR1 family protein
XP_024958986.1FAR1 family protein
XP_024958987.1FAR1 family protein
XP_024959010.1FAR1 family protein
XP_024961018.1FAR1 family protein
XP_024961086.1FAR1 family protein
XP_024961489.1FAR1 family protein
XP_024961490.1FAR1 family protein
XP_024961491.1FAR1 family protein
XP_024961492.1FAR1 family protein
XP_024962514.1FAR1 family protein
XP_024962583.1FAR1 family protein
XP_024962776.1FAR1 family protein
XP_024962943.1FAR1 family protein
XP_024962992.1FAR1 family protein
XP_024963208.1FAR1 family protein
XP_024963482.1FAR1 family protein
XP_024963894.1FAR1 family protein
XP_024963980.1FAR1 family protein
XP_024963981.1FAR1 family protein
XP_024963983.1FAR1 family protein
XP_024963984.1FAR1 family protein
XP_024964182.1FAR1 family protein
XP_024964420.1FAR1 family protein
XP_024964501.1FAR1 family protein
XP_024964557.1FAR1 family protein
XP_024964573.1FAR1 family protein
XP_024965336.1FAR1 family protein
XP_024965337.1FAR1 family protein
XP_024965434.1FAR1 family protein
XP_024965625.1FAR1 family protein
XP_024965781.1FAR1 family protein
XP_024965787.1FAR1 family protein
XP_024965867.1FAR1 family protein
XP_024966005.1FAR1 family protein
XP_024966085.1FAR1 family protein
XP_024966126.1FAR1 family protein
XP_024966167.1FAR1 family protein
XP_024966327.1FAR1 family protein
XP_024966463.1FAR1 family protein
XP_024968307.1FAR1 family protein
XP_024968308.1FAR1 family protein
XP_024968737.1FAR1 family protein
XP_024969199.1FAR1 family protein
XP_024969595.1FAR1 family protein
XP_024969705.1FAR1 family protein
XP_024969722.1FAR1 family protein
XP_024971351.1FAR1 family protein
XP_024972172.1FAR1 family protein
XP_024974727.1FAR1 family protein
XP_024974809.1FAR1 family protein
XP_024974842.1FAR1 family protein
XP_024974846.1FAR1 family protein
XP_024975695.1FAR1 family protein
XP_024976183.1FAR1 family protein
XP_024976210.1FAR1 family protein
XP_024976220.1FAR1 family protein
XP_024977611.1FAR1 family protein
XP_024977623.1FAR1 family protein
XP_024977633.1FAR1 family protein
XP_024977644.1FAR1 family protein
XP_024977645.1FAR1 family protein
XP_024978964.1FAR1 family protein
XP_024979005.1FAR1 family protein
XP_024980158.1FAR1 family protein
XP_024980834.1FAR1 family protein
XP_024980839.1FAR1 family protein
XP_024980843.1FAR1 family protein
XP_024980934.1FAR1 family protein
XP_024982429.1FAR1 family protein
XP_024982772.1FAR1 family protein
XP_024982773.1FAR1 family protein
XP_024982774.1FAR1 family protein
XP_024982775.1FAR1 family protein
XP_024982948.1FAR1 family protein
XP_024984003.1FAR1 family protein
XP_024984098.1FAR1 family protein
XP_024984872.1FAR1 family protein
XP_024984873.1FAR1 family protein
XP_024984874.1FAR1 family protein
XP_024984875.1FAR1 family protein
XP_024985467.1FAR1 family protein
XP_024986537.1FAR1 family protein
XP_024987028.1FAR1 family protein
XP_024988093.1FAR1 family protein
XP_024988220.1FAR1 family protein
XP_024988459.1FAR1 family protein
XP_024988941.1FAR1 family protein
XP_024988942.1FAR1 family protein
XP_024988943.1FAR1 family protein
XP_024988944.1FAR1 family protein
XP_024988945.1FAR1 family protein
XP_024988946.1FAR1 family protein
XP_024989154.1FAR1 family protein
XP_024989264.1FAR1 family protein
XP_024989282.1FAR1 family protein
XP_024989314.1FAR1 family protein
XP_024990517.1FAR1 family protein
XP_024990545.1FAR1 family protein
XP_024990577.1FAR1 family protein
XP_024990610.1FAR1 family protein
XP_024990644.1FAR1 family protein
XP_024990723.1FAR1 family protein
XP_024990735.1FAR1 family protein
XP_024990995.1FAR1 family protein
XP_024990996.1FAR1 family protein
XP_024990998.1FAR1 family protein
XP_024990999.1FAR1 family protein
XP_024992108.1FAR1 family protein
XP_024992109.1FAR1 family protein
XP_024992110.1FAR1 family protein
XP_024992461.1FAR1 family protein
XP_024993925.1FAR1 family protein
XP_024995241.1FAR1 family protein
XP_024995247.1FAR1 family protein
XP_024995856.1FAR1 family protein
XP_024995898.1FAR1 family protein
XP_024996074.1FAR1 family protein
XP_024996779.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885