PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Chara braunii
bZIP Family
Species TF ID Description
GBG61875.1bZIP family protein
GBG62149.1bZIP family protein
GBG62507.1bZIP family protein
GBG66131.1bZIP family protein
GBG68320.1bZIP family protein
GBG68321.1bZIP family protein
GBG68382.1bZIP family protein
GBG71541.1bZIP family protein
GBG71997.1bZIP family protein
GBG71998.1bZIP family protein
GBG71999.1bZIP family protein
GBG72000.1bZIP family protein
GBG74331.1bZIP family protein
GBG76658.1bZIP family protein
GBG79318.1bZIP family protein
GBG79321.1bZIP family protein
GBG79323.1bZIP family protein
GBG85980.1bZIP family protein
GBG87885.1bZIP family protein
GBG93385.1bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833