PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Zea mays
NF-YA Family
Species TF ID Description
GRMZM2G000686_P01NF-YA family protein
GRMZM2G000686_P02NF-YA family protein
GRMZM2G000686_P03NF-YA family protein
GRMZM2G000686_P04NF-YA family protein
GRMZM2G000686_P05NF-YA family protein
GRMZM2G000686_P06NF-YA family protein
GRMZM2G000686_P08NF-YA family protein
GRMZM2G000686_P10NF-YA family protein
GRMZM2G026157_P01NF-YA family protein
GRMZM2G037630_P01NF-YA family protein
GRMZM2G038303_P01NF-YA family protein
GRMZM2G040349_P01NF-YA family protein
GRMZM2G040349_P02NF-YA family protein
GRMZM2G091964_P01NF-YA family protein
GRMZM2G091964_P02NF-YA family protein
GRMZM2G091964_P03NF-YA family protein
GRMZM2G096016_P01NF-YA family protein
GRMZM2G096016_P02NF-YA family protein
GRMZM2G104396_P01NF-YA family protein
GRMZM2G126957_P01NF-YA family protein
GRMZM2G126957_P02NF-YA family protein
GRMZM2G165488_P01NF-YA family protein
GRMZM2G165488_P02NF-YA family protein
GRMZM2G165488_P03NF-YA family protein
GRMZM2G165488_P04NF-YA family protein
GRMZM2G361842_P01NF-YA family protein
GRMZM2G361842_P02NF-YA family protein
GRMZM2G582893_P01NF-YA family protein
GRMZM5G829103_P03NF-YA family protein
GRMZM5G829103_P05NF-YA family protein
GRMZM5G829103_P06NF-YA family protein
GRMZM5G829103_P07NF-YA family protein
GRMZM5G853836_P02NF-YA family protein
GRMZM5G857944_P01NF-YA family protein
GRMZM5G857944_P02NF-YA family protein
GRMZM5G865626_P01NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982