PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Zea mays
HSF Family
Species TF ID Description
AC205471.4_FGP003HSF family protein
AC206165.3_FGP007HSF family protein
AC216247.3_FGP001HSF family protein
GRMZM2G002131_P01HSF family protein
GRMZM2G003489_P03HSF family protein
GRMZM2G005815_P01HSF family protein
GRMZM2G005815_P02HSF family protein
GRMZM2G010871_P01HSF family protein
GRMZM2G010871_P02HSF family protein
GRMZM2G010871_P03HSF family protein
GRMZM2G010871_P05HSF family protein
GRMZM2G025685_P01HSF family protein
GRMZM2G025685_P02HSF family protein
GRMZM2G026742_P01HSF family protein
GRMZM2G026742_P02HSF family protein
GRMZM2G026742_P03HSF family protein
GRMZM2G026742_P04HSF family protein
GRMZM2G059851_P01HSF family protein
GRMZM2G086880_P01HSF family protein
GRMZM2G088242_P01HSF family protein
GRMZM2G089525_P01HSF family protein
GRMZM2G098696_P01HSF family protein
GRMZM2G098696_P02HSF family protein
GRMZM2G105348_P01HSF family protein
GRMZM2G115456_P01HSF family protein
GRMZM2G118047_P01HSF family protein
GRMZM2G118047_P02HSF family protein
GRMZM2G118453_P01HSF family protein
GRMZM2G118485_P01HSF family protein
GRMZM2G118485_P02HSF family protein
GRMZM2G125969_P01HSF family protein
GRMZM2G125969_P02HSF family protein
GRMZM2G132971_P01HSF family protein
GRMZM2G132971_P02HSF family protein
GRMZM2G139535_P01HSF family protein
GRMZM2G139535_P02HSF family protein
GRMZM2G164909_P01HSF family protein
GRMZM2G165272_P01HSF family protein
GRMZM2G165972_P02HSF family protein
GRMZM2G165972_P03HSF family protein
GRMZM2G165972_P04HSF family protein
GRMZM2G173090_P01HSF family protein
GRMZM2G173090_P02HSF family protein
GRMZM2G179802_P01HSF family protein
GRMZM2G179802_P02HSF family protein
GRMZM2G179802_P03HSF family protein
GRMZM2G301485_P01HSF family protein
GRMZM2G384339_P01HSF family protein
GRMZM2G384339_P02HSF family protein
HSF Family Introduction

Heat stress transcription factors (Hsfs) are the major regulators of the plant heat stress (hs) response. Sequencing of the Arabidopsis genome revealed the existence of 21 open-reading frames (ORFs) encoding putative Hsfs assigned to classes A-C. Here we present results of a functional genomics approach to the Arabidopsis Hsf family focused on the analysis of their C-terminal domains (CTDs) harboring conserved modules for their function as transcription factors and their intracellular localization. Using reporter assays in tobacco protoplasts and yeast as well as glutathione-S-transferase (GST) pull-down assays, we demonstrate that short peptide motifs enriched with aromatic and large hydrophobic amino acid (aa) residues embedded in an acidic surrounding (AHA motifs) are essential for transcriptional activity of class A Hsfs. In contrast to this, class B and C Hsfs lack AHA motifs and have no activator function on their own. We also provide evidence for the function of a leucine (Leu)-rich region centered around a conserved QMGΦL motif at the very C-terminus as a nuclear export signal (NES) of class A Hsfs. Sequence comparison indicates that the combination of a C-terminal AHA motif with the consensus sequence FWxxF/L,F/I/L as well as the adjacent NES represents a signature domain for plant class A Hsfs, which allowed to identify more than 60 new Hsfs from the expressed sequence tag (EST) database.

Kotak S, Port M, Ganguli A, Bicker F, von Koskull-Doring P.
Characterization of C-terminal domains of Arabidopsis heat stress transcription factors (Hsfs) and identification of a new signature combination of plant class A Hsfs with AHA and NES motifs essential for activator function and intracellular localization.
Plant J, 2004. 39(1): p. 98-112.
PMID: 15200645