PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Zea mays
BES1 Family
Species TF ID Description
AC194970.5_FGP002BES1 family protein
GRMZM2G069486_P01BES1 family protein
GRMZM2G069486_P02BES1 family protein
GRMZM2G069486_P03BES1 family protein
GRMZM2G102514_P01BES1 family protein
GRMZM2G152172_P01BES1 family protein
GRMZM2G307241_P01BES1 family protein
GRMZM2G307241_P02BES1 family protein
GRMZM2G369018_P01BES1 family protein
GRMZM2G446515_P03BES1 family protein
GRMZM2G446515_P04BES1 family protein
GRMZM2G446515_P05BES1 family protein
GRMZM2G446515_P06BES1 family protein
GRMZM5G812774_P01BES1 family protein
GRMZM5G852801_P01BES1 family protein
GRMZM5G868061_P01BES1 family protein
GRMZM6G287292_P01BES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330