PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Ziziphus jujuba
SBP Family
Species TF ID Description
XP_015867006.1SBP family protein
XP_015868798.1SBP family protein
XP_015871759.1SBP family protein
XP_015871760.1SBP family protein
XP_015871761.1SBP family protein
XP_015871763.1SBP family protein
XP_015871790.1SBP family protein
XP_015871791.1SBP family protein
XP_015871792.1SBP family protein
XP_015871793.1SBP family protein
XP_015871794.1SBP family protein
XP_015871795.1SBP family protein
XP_015871796.1SBP family protein
XP_015871797.1SBP family protein
XP_015871799.1SBP family protein
XP_015871800.1SBP family protein
XP_015871801.1SBP family protein
XP_015871802.1SBP family protein
XP_015872096.1SBP family protein
XP_015872841.1SBP family protein
XP_015872885.1SBP family protein
XP_015879984.1SBP family protein
XP_015880440.1SBP family protein
XP_015881660.1SBP family protein
XP_015882190.1SBP family protein
XP_015882191.1SBP family protein
XP_015883292.1SBP family protein
XP_015887397.1SBP family protein
XP_015887398.1SBP family protein
XP_015888326.1SBP family protein
XP_015888327.1SBP family protein
XP_015889429.1SBP family protein
XP_015889430.1SBP family protein
XP_015889537.1SBP family protein
XP_015890482.1SBP family protein
XP_015891807.1SBP family protein
XP_015891808.1SBP family protein
XP_015891809.1SBP family protein
XP_015894286.1SBP family protein
XP_015894287.1SBP family protein
XP_015894315.1SBP family protein
XP_015894316.1SBP family protein
XP_015894317.1SBP family protein
XP_015894319.1SBP family protein
XP_015895206.1SBP family protein
XP_015898941.1SBP family protein
XP_015898942.1SBP family protein
XP_015899233.1SBP family protein
XP_015900129.1SBP family protein
SBP Family Introduction

SQUAMOSA promoter binding proteins (SBPs) form a major family of plant-specific transcription factors related to flower development. Although SBPs are heterogeneous in primary structure, they share a highly conserved DNA-binding domain (DBD) that has been suggested to be zinc binding. Here we report the NMR solution structures of DBDs of two SBPs of Arabidopsis thaliana, SPL4 and SPL7. The two share essentially the same structural features. Each structure contains two zinc-binding sites consisting of eight Cys or His residues in a Cys3HisCys2HisCys or Cys6HisCys sequence motif in which the first four residues coordinate to one zinc and the last four coordinate to the other. These structures are dissimilar to other known zinc-binding structures, and thus represent a novel type of zinc-binding motif. The electrostatic profile on the surface suggested that a continuous region, including all the conserved basic residues, is involved in the DNA binding, the mode of which is likely to be novel as well.

Yamasaki K, Kigawa T, Inoue M, Tateno M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Nunokawa E, Ishizuka Y, Terada T, Shirouzu M, Osanai T, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
A novel zinc-binding motif revealed by solution structures of DNA-binding domains of Arabidopsis SBP-family transcription factors
J Mol Biol. 2004 Mar 12;337(1):49-63.
PMID: 15001351

SBP-box genes were first characterized as SQUAMOSA promoter binding proteins (SBPs) to regulate the expression of MADS-box genes in early flower development of A. majus (Klein et al., 1996). Since then, SBP-box genes have been identified in many plants including green alga, moss, silver birch, A. majus, Arabidopsis and maize. They play critical roles in regulating flower and fruit development as well as other physiological processes ([Moreno et al., 1997],[Eriksson et al., 2004], [Lannenpaa et al., 2004], [Arazi et al., 2005] and [Kropat et al., 2005]). It has been reported that Arabidopsis SPL3, SPL8 and SPL14 involves in flowering, sporogenesis, GA signaling and toxin resistance ([Cardon et al., 1997], [Unte et al., 2003], [Stone et al., 2005] and [Zhang et al., 2006]) while maize tga1 and tomato LeSPL-CNR affect fruit development ([Wang et al., 2005a] and [Manning et al., 2006]).

SBP-box genes encode proteins sharing a conserved DNA-binding domain of 79 amino acid residues. It has been proved that the DNA-binding domain of SBP-box genes is necessary and sufficient to bind to a palindromic GTAC core motif ([Klein et al., 1996], [Cardon et al., 1997], [Cardon et al., 1999], [Lannenpaa et al., 2004] and [Birkenbihl et al., 2005]). Studies on the NMR solution structure of the fragment of Arabidopsis SPL4 and SPL7 revealed that the DNA-binding domain of SBPs consisted of two separate zinc-binding sites. One zinc finger is C3H or C4 and the other is C2HC (Yamasaki et al., 2004 K. Yamasaki et al.,).

Guo AY, Zhu QH, Gu X, Ge S, Yang J, Luo J.
Genome-wide identification and evolutionary analysis of the plant specific SBP-box transcription factor family.
Gene. 2008 Jul 15;418(1-2):1-8.
PMID: 18495384