PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Ziziphus jujuba
E2F/DP Family
Species TF ID Description
XP_015867952.1E2F/DP family protein
XP_015867953.1E2F/DP family protein
XP_015868389.1E2F/DP family protein
XP_015868390.1E2F/DP family protein
XP_015873117.1E2F/DP family protein
XP_015878522.1E2F/DP family protein
XP_015878523.1E2F/DP family protein
XP_015878524.1E2F/DP family protein
XP_015879213.1E2F/DP family protein
XP_015879214.1E2F/DP family protein
XP_015879215.1E2F/DP family protein
XP_015879579.1E2F/DP family protein
XP_015898821.1E2F/DP family protein
XP_015898822.1E2F/DP family protein
XP_015902932.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710