PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

Plant Transcription Factor Database

Triticum aestivum

NF-YA Family

Species	TF ID	Description
Triticum aestivum (22)	Traes_2AS_7C177F9DB.1	NF-YA family protein
	Traes_2BS_A95B28510.1	NF-YA family protein
	Traes_2DS_69FBC78BC.2	NF-YA family protein
	Traes_4AL_7C4C68FD0.2	NF-YA family protein
	Traes_4AS_2603E68AF.3	NF-YA family protein
	Traes_4BL_7DA93696E.1	NF-YA family protein
	Traes_4BS_B7B7EFF37.1	NF-YA family protein
	Traes_4DL_8156B39DF.1	NF-YA family protein
	Traes_4DS_AFBE29C20.2	NF-YA family protein
	Traes_5AL_047ABC9FC.1	NF-YA family protein
	Traes_5AS_178725FAF.2	NF-YA family protein
	Traes_5AS_378F353CF.2	NF-YA family protein
	Traes_5BL_B5F4BA2FD.2	NF-YA family protein
	Traes_5BS_49C7C1976.2	NF-YA family protein
	Traes_5BS_F1DE20B4B.1	NF-YA family protein
	Traes_5DL_7F3ABFDD6.1	NF-YA family protein
	Traes_5DS_443F1993A.2	NF-YA family protein
	Traes_5DS_5B1AB0AD3.2	NF-YA family protein
	Traes_6AL_C0E74F959.2	NF-YA family protein
	Traes_6BL_953171851.2	NF-YA family protein
	Traes_6DL_29F162FB2.2	NF-YA family protein
	Traes_6DL_FD903DBD8.1	NF-YA family protein

NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982