PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Sphagnum fallax
WRKY Family
Species TF ID Description
Sphfalx0000s0074.1.pWRKY family protein
Sphfalx0001s0238.1.pWRKY family protein
Sphfalx0001s0394.1.pWRKY family protein
Sphfalx0010s0133.1.pWRKY family protein
Sphfalx0011s0091.1.pWRKY family protein
Sphfalx0011s0144.1.pWRKY family protein
Sphfalx0023s0146.1.pWRKY family protein
Sphfalx0025s0145.1.pWRKY family protein
Sphfalx0029s0016.1.pWRKY family protein
Sphfalx0033s0087.1.pWRKY family protein
Sphfalx0043s0004.1.pWRKY family protein
Sphfalx0044s0073.1.pWRKY family protein
Sphfalx0045s0049.1.pWRKY family protein
Sphfalx0055s0023.1.pWRKY family protein
Sphfalx0055s0061.1.pWRKY family protein
Sphfalx0055s0091.1.pWRKY family protein
Sphfalx0071s0028.1.pWRKY family protein
Sphfalx0071s0030.1.pWRKY family protein
Sphfalx0077s0031.1.pWRKY family protein
Sphfalx0080s0048.1.pWRKY family protein
Sphfalx0080s0048.2.pWRKY family protein
Sphfalx0083s0052.1.pWRKY family protein
Sphfalx0093s0087.1.pWRKY family protein
Sphfalx0098s0074.1.pWRKY family protein
Sphfalx0100s0074.1.pWRKY family protein
Sphfalx0101s0045.1.pWRKY family protein
Sphfalx0101s0045.2.pWRKY family protein
Sphfalx0118s0017.1.pWRKY family protein
Sphfalx0124s0044.1.pWRKY family protein
Sphfalx0124s0044.2.pWRKY family protein
Sphfalx0158s0026.1.pWRKY family protein
Sphfalx0190s0021.1.pWRKY family protein
Sphfalx0197s0013.1.pWRKY family protein
Sphfalx0199s0019.1.pWRKY family protein
Sphfalx0206s0037.1.pWRKY family protein
Sphfalx0226s0009.1.pWRKY family protein
Sphfalx0253s0015.1.pWRKY family protein
Sphfalx0291s0003.1.pWRKY family protein
Sphfalx0407s0004.1.pWRKY family protein
Sphfalx0438s0004.1.pWRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701