PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Sphagnum fallax
ARF Family
Species TF ID Description
Sphfalx0001s0160.1.pARF family protein
Sphfalx0002s0406.1.pARF family protein
Sphfalx0027s0084.1.pARF family protein
Sphfalx0027s0084.2.pARF family protein
Sphfalx0079s0065.1.pARF family protein
Sphfalx0095s0033.1.pARF family protein
Sphfalx0100s0020.1.pARF family protein
Sphfalx0120s0001.1.pARF family protein
Sphfalx0153s0039.1.pARF family protein
Sphfalx0185s0016.1.pARF family protein
Sphfalx0299s0001.1.pARF family protein
ARF Family Introduction

Auxin response factors (ARF) are transcription factors that regulate the expression of auxin response genes. ARFs bind with specificity to TGTCTC auxin response elements (AuxRE) in promoters of these genes and function in combination with Aux/IAA (auxin/indole acetic acid) repressors, which dimerize with ARF activators in an auxin-regulated manner.

Most ARFs consist of an amino-terminal DNA-binding domain (DBD), a middle region that functions as an activation domain (AD) or repression domain (RD), and a carboxy-terminal dimerization domain (CTD). The ARF DBD is classified as a plant-specific B3-type, but requires additional amino-terminal and carboxy-terminal amino acids for efficient in vitro binding to TGTCTC AuxREs.

The ARF ADs and RDs are located just carboxy-terminal to the DBDs and contain biased amino acid sequences. ARF ADs are enriched in glutamine along with serine and leucine residues, while ARF RDs are enriched in serine, proline, leucine and glycine residues.

Guilfoyle TJ, Hagen G.
Auxin response factors.
Curr Opin Plant Biol, 2007. 10(5): p. 453-60.
PMID: 17900969