PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Raphanus raphanistrum
WOX Family
Species TF ID Description
RrC10171_p1WOX family protein
RrC12464_p1WOX family protein
RrC12997_p1WOX family protein
RrC13730_p1WOX family protein
RrC14403_p1WOX family protein
RrC16300_p1WOX family protein
RrC17125_p1WOX family protein
RrC17554_p1WOX family protein
RrC23237_p1WOX family protein
RrC2427_p1WOX family protein
RrC2455_p2WOX family protein
RrC26857_p1WOX family protein
RrC31_p9WOX family protein
RrC3262_p3WOX family protein
RrC3292_p1WOX family protein
RrC434_p6WOX family protein
RrC4410_p2WOX family protein
RrC546_p1WOX family protein
RrC587_p1WOX family protein
RrC599_p1WOX family protein
RrC7317_p1WOX family protein
RrC8152_p1WOX family protein
RrC8563_p1WOX family protein
RrC8923_p2WOX family protein
RrC926_p1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590