PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Raphanus raphanistrum
NF-YB Family
Species TF ID Description
RrC11964_p1NF-YB family protein
RrC1214_p2NF-YB family protein
RrC12404_p1NF-YB family protein
RrC20063_p1NF-YB family protein
RrC2196_p2NF-YB family protein
RrC2292_p5NF-YB family protein
RrC2292_p7NF-YB family protein
RrC264_p1NF-YB family protein
RrC28148_p1NF-YB family protein
RrC3475_p4NF-YB family protein
RrC3475_p5NF-YB family protein
RrC3662_p1NF-YB family protein
RrC3704_p3NF-YB family protein
RrC3968_p2NF-YB family protein
RrC4944_p4NF-YB family protein
RrC5150_p1NF-YB family protein
RrC5805_p1NF-YB family protein
RrC59920_p1NF-YB family protein
RrC6027_p3NF-YB family protein
RrC69_p3NF-YB family protein
RrC7464_p1NF-YB family protein
RrC768_p5NF-YB family protein
RrC8778_p1NF-YB family protein
RrC992_p7NF-YB family protein
NF-YB Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

As with NF-YA, NF-YB and NF-YC families have well-described subunit interaction and DNA-binding domains ( Kim et al., 1996; Sinha et al., 1996; McNabb et al., 1997; Romier et al., 2003). The conserved regions of NF-YB and NF-YC have structural and amino acid homology to histone fold motifs. Specifically, NF-YB is related to the histone fold motifs of H2B histones, while NF-YC subunits are related to H2A histones (Mantovani, 1999).

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982