PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Pseudotsuga menziesii
bZIP Family
Species TF ID Description
PSME_00000011-RAbZIP family protein
PSME_00001258-RAbZIP family protein
PSME_00001522-RAbZIP family protein
PSME_00004075-RAbZIP family protein
PSME_00008136-RAbZIP family protein
PSME_00012248-RAbZIP family protein
PSME_00013026-RAbZIP family protein
PSME_00016648-RAbZIP family protein
PSME_00018083-RAbZIP family protein
PSME_00021307-RAbZIP family protein
PSME_00021789-RAbZIP family protein
PSME_00022194-RAbZIP family protein
PSME_00023078-RAbZIP family protein
PSME_00024681-RAbZIP family protein
PSME_00031462-RAbZIP family protein
PSME_00032287-RAbZIP family protein
PSME_00034268-RAbZIP family protein
PSME_00041126-RAbZIP family protein
PSME_00044284-RAbZIP family protein
PSME_00047601-RAbZIP family protein
PSME_00047878-RAbZIP family protein
PSME_00048048-RAbZIP family protein
PSME_00049092-RAbZIP family protein
PSME_00049459-RAbZIP family protein
PSME_00049819-RAbZIP family protein
PSME_00053172-RAbZIP family protein
PSME_00054353-RAbZIP family protein
PSME_00056943-RAbZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833