PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Phyllostachys heterocycla
E2F/DP Family
Species TF ID Description
PH01000010G3150E2F/DP family protein
PH01000567G0450E2F/DP family protein
PH01000705G0580E2F/DP family protein
PH01001325G0370E2F/DP family protein
PH01001390G0020E2F/DP family protein
PH01001688G0260E2F/DP family protein
PH01001918G0120E2F/DP family protein
PH01002448G0160E2F/DP family protein
PH01002896G0090E2F/DP family protein
PH01003957G0030E2F/DP family protein
PH01004826G0040E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710