PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Phoenix dactylifera
FAR1 Family
Species TF ID Description
PDK_30s1022651g002FAR1 family protein
PDK_30s1022651g003FAR1 family protein
PDK_30s1029841g001FAR1 family protein
PDK_30s1031941g003FAR1 family protein
PDK_30s1042271g004FAR1 family protein
PDK_30s1051821g002FAR1 family protein
PDK_30s1051821g003FAR1 family protein
PDK_30s1080341g002FAR1 family protein
PDK_30s1100981g006FAR1 family protein
PDK_30s1113891g001FAR1 family protein
PDK_30s1147161g001FAR1 family protein
PDK_30s1150431g002FAR1 family protein
PDK_30s1153071g001FAR1 family protein
PDK_30s1155011g003FAR1 family protein
PDK_30s1191211g001FAR1 family protein
PDK_30s1202321g002FAR1 family protein
PDK_30s654821g002FAR1 family protein
PDK_30s6550916g003FAR1 family protein
PDK_30s659791g002FAR1 family protein
PDK_30s670221g003FAR1 family protein
PDK_30s674441g001FAR1 family protein
PDK_30s679431g003FAR1 family protein
PDK_30s701551g002FAR1 family protein
PDK_30s701651g002FAR1 family protein
PDK_30s722581g001FAR1 family protein
PDK_30s744692g001FAR1 family protein
PDK_30s755021g005FAR1 family protein
PDK_30s755021g007FAR1 family protein
PDK_30s762671g002FAR1 family protein
PDK_30s766431g001FAR1 family protein
PDK_30s772411g001FAR1 family protein
PDK_30s779311g005FAR1 family protein
PDK_30s821521g001FAR1 family protein
PDK_30s839611g001FAR1 family protein
PDK_30s844271g003FAR1 family protein
PDK_30s854901g001FAR1 family protein
PDK_30s866091g002FAR1 family protein
PDK_30s868311g001FAR1 family protein
PDK_30s875851g001FAR1 family protein
PDK_30s883821g016FAR1 family protein
PDK_30s889901g007FAR1 family protein
PDK_30s893541g001FAR1 family protein
PDK_30s911131g003FAR1 family protein
PDK_30s914011g002FAR1 family protein
PDK_30s929081g003FAR1 family protein
PDK_30s929081g004FAR1 family protein
PDK_30s934911g004FAR1 family protein
PDK_30s994951g001FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885