PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Ocimum tenuiflorum
AP2 Family
Species TF ID Description
Ote100003060011AP2 family protein
Ote100021710041AP2 family protein
Ote100028450031AP2 family protein
Ote100047180061AP2 family protein
Ote100049970041AP2 family protein
Ote100061770021AP2 family protein
Ote100063230091AP2 family protein
Ote100090380011AP2 family protein
Ote100096710011AP2 family protein
Ote100098110081AP2 family protein
Ote100105480101AP2 family protein
Ote100105480151AP2 family protein
Ote100125760111AP2 family protein
Ote100126110151AP2 family protein
Ote100134790011AP2 family protein
Ote100150920011AP2 family protein
Ote100150920061AP2 family protein
Ote100158750081AP2 family protein
Ote100173560001AP2 family protein
Ote100202400041AP2 family protein
Ote100214300091AP2 family protein
Ote100217740121AP2 family protein
Ote100222510011AP2 family protein
Ote100227520111AP2 family protein
Ote100229580121AP2 family protein
Ote100229580171AP2 family protein
Ote100230740051AP2 family protein
Ote100231160061AP2 family protein
Ote100231240071AP2 family protein
Ote100231600061AP2 family protein
Ote100267120021AP2 family protein
Ote100272460061AP2 family protein
Ote237292390011AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444

Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102