PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Oryza punctata
Species TF ID Description
OPUNC01G29290.1MIKC_MADS family protein
OPUNC01G38250.1MIKC_MADS family protein
OPUNC01G38480.1MIKC_MADS family protein
OPUNC01G38480.2MIKC_MADS family protein
OPUNC02G00040.1MIKC_MADS family protein
OPUNC02G00040.2MIKC_MADS family protein
OPUNC02G04560.1MIKC_MADS family protein
OPUNC02G19600.1MIKC_MADS family protein
OPUNC02G25740.1MIKC_MADS family protein
OPUNC02G29000.1MIKC_MADS family protein
OPUNC02G29000.2MIKC_MADS family protein
OPUNC02G29000.3MIKC_MADS family protein
OPUNC02G29000.4MIKC_MADS family protein
OPUNC02G30720.1MIKC_MADS family protein
OPUNC03G01630.1MIKC_MADS family protein
OPUNC03G01630.2MIKC_MADS family protein
OPUNC03G01630.3MIKC_MADS family protein
OPUNC03G01630.4MIKC_MADS family protein
OPUNC03G01630.5MIKC_MADS family protein
OPUNC03G01630.6MIKC_MADS family protein
OPUNC03G06100.1MIKC_MADS family protein
OPUNC03G08100.1MIKC_MADS family protein
OPUNC03G31590.1MIKC_MADS family protein
OPUNC03G31590.2MIKC_MADS family protein
OPUNC03G31610.1MIKC_MADS family protein
OPUNC04G05760.1MIKC_MADS family protein
OPUNC04G05760.2MIKC_MADS family protein
OPUNC04G11660.1MIKC_MADS family protein
OPUNC04G20380.1MIKC_MADS family protein
OPUNC04G20380.2MIKC_MADS family protein
OPUNC04G22650.1MIKC_MADS family protein
OPUNC04G22650.2MIKC_MADS family protein
OPUNC05G06200.1MIKC_MADS family protein
OPUNC06G04000.1MIKC_MADS family protein
OPUNC06G07080.1MIKC_MADS family protein
OPUNC06G07080.2MIKC_MADS family protein
OPUNC06G13170.1MIKC_MADS family protein
OPUNC06G21840.1MIKC_MADS family protein
OPUNC06G24880.1MIKC_MADS family protein
OPUNC07G00470.1MIKC_MADS family protein
OPUNC07G20110.1MIKC_MADS family protein
OPUNC08G01030.1MIKC_MADS family protein
OPUNC08G13690.1MIKC_MADS family protein
OPUNC08G13690.2MIKC_MADS family protein
OPUNC08G19670.1MIKC_MADS family protein
OPUNC08G19670.2MIKC_MADS family protein
OPUNC08G19670.3MIKC_MADS family protein
OPUNC08G19670.4MIKC_MADS family protein
OPUNC08G19670.5MIKC_MADS family protein
OPUNC08G19670.6MIKC_MADS family protein
OPUNC09G14150.1MIKC_MADS family protein
OPUNC09G14150.2MIKC_MADS family protein
OPUNC09G14150.3MIKC_MADS family protein
OPUNC09G14150.4MIKC_MADS family protein
OPUNC09G14150.5MIKC_MADS family protein
OPUNC10G15300.1MIKC_MADS family protein
OPUNC12G05650.1MIKC_MADS family protein
OPUNC12G05660.1MIKC_MADS family protein
OPUNC12G05660.2MIKC_MADS family protein
OPUNC12G05660.3MIKC_MADS family protein
OPUNC12G11630.1MIKC_MADS family protein
MIKC_MADS (MIKC-type MADS) Family Introduction

The best studied plant MADS-box transcription factors are those involved in floral organ identity determination. Analysis of homeotic floral mutants resulted in the formulation of a genetic model, named the ABC model, that explains how the combined functions of three classes of genes (A, B, and C) determine the identity of the four flower organs (reviewed by Coen and Meyerowitz, 1991). Arabidopsis has two A-class genes (AP1 and AP2 [Bowman et al., 1989]), two B-class genes (PI and AP3), and a single C-class gene (AG), of which only AP2 is not a MADS-box gene. Recently, it was shown that the Arabidopsis B- and C-function genes, which control petal, stamen, and carpel development, are functionally dependent on three highly similar MADS-box genes, SEP1, SEP2, and SEP3 (Pelaz et al., 2000). Interestingly, only when mutant knockout alleles of the three SEP genes were combined in a triple sep1 sep2 sep3 mutant was loss of petal, stamen, and carpel identity observed, resulting in a flower composed of only sepals. This example shows that redundancy occurs in the MADS-box gene family, which complicates reverse genetic strategies for gene function analysis. The SHP genes provide another example of MADS-box gene redundancy. shp1 and shp2 single mutants do not exhibit any phenotypic effect, whereas in the double mutant, development of the dehiscence zone is disturbed in the fruit, resulting in a failure to release seeds (Liljegren et al., 2000)[1].

It has been proposed that there are at least 2 lineages (type I and type II) of MADS-box genes in plants, animals, and fungi. Most of the well-studied plant genes are type II genes and have three more domains than type I genes from the N to the C terminus of the protein:intervening (I) domain (~30 codons), keratin-lik e coiled-coil (K) domain (~70 codons), and Cterminal (C) domain (variable length). These genes are called the MIKC-type and are specific to plants[2].

The MADS-box is a DNA binding domain of 58 amino acids that binds DNA at consensus recognition sequences known as CArG boxes [CC(A/T)6GG] (Hayes et al., 1988; Riechmann et al., 1996b). The interaction with DNA has been studied in detail for the human and yeast MADS-box proteins thanks to the resolved crystal structures (Pellegrini et al., 1995; Santelli and Richmond, 2000). The I domain is less conserved and contributes to the specification of dimerization. The K domain is characterized by a coiled-coil structure, which facilitates the dimerization of MADS-box proteins (Davies et al., 1996; Fan et al., 1997). The C domain is the least conserved domain; in some cases, it has been shown to contain a transactivation domain or to contribute to the formation of multimeric MADS-box protein complexes (Egea-Cortines et al., 1999; Honma and Goto, 2001)[1].

1.Parenicova L, de Folter S, Kieffer M, Horner DS, Favalli C, Busscher J, Cook HE, Ingram RM, Kater MM, Davies B, Angenent GC, Colombo L.
Molecular and phylogenetic analyses of the complete MADS-box transcription factor family in Arabidopsis: new openings to the MADS world.
Plant Cell. 2003 Jul;15(7):1538-51.
PMID: 12837945
2.Nam J, dePamphilis CW, Ma H, Nei M.
Antiquity and evolution of the MADS-box gene family controlling flower development in plants.
Mol Biol Evol. 2003 Sep;20(9):1435-47. Epub 2003 May 30.
PMID: 12777513