PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Oryza barthii
E2F/DP Family
Species TF ID Description
OBART01G26520.1E2F/DP family protein
OBART02G19430.1E2F/DP family protein
OBART02G31930.1E2F/DP family protein
OBART02G31930.2E2F/DP family protein
OBART03G04060.1E2F/DP family protein
OBART04G00680.1E2F/DP family protein
OBART04G12180.1E2F/DP family protein
OBART06G09260.1E2F/DP family protein
OBART10G11350.1E2F/DP family protein
OBART12G03570.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710