PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Nicotiana tabacum
GRF Family
Species TF ID Description
XP_016437615.1GRF family protein
XP_016438848.1GRF family protein
XP_016444360.1GRF family protein
XP_016445515.1GRF family protein
XP_016446976.1GRF family protein
XP_016446980.1GRF family protein
XP_016447733.1GRF family protein
XP_016449439.1GRF family protein
XP_016449440.1GRF family protein
XP_016458652.1GRF family protein
XP_016458658.1GRF family protein
XP_016459153.1GRF family protein
XP_016473091.1GRF family protein
XP_016473165.1GRF family protein
XP_016474877.1GRF family protein
XP_016477805.1GRF family protein
XP_016478447.1GRF family protein
XP_016478448.1GRF family protein
XP_016481857.1GRF family protein
XP_016481858.1GRF family protein
XP_016481859.1GRF family protein
XP_016488378.1GRF family protein
XP_016493536.1GRF family protein
XP_016493537.1GRF family protein
XP_016493830.1GRF family protein
XP_016497921.1GRF family protein
XP_016505401.1GRF family protein
XP_016506106.1GRF family protein
XP_016506107.1GRF family protein
XP_016507606.1GRF family protein
XP_016507607.1GRF family protein
XP_016507608.1GRF family protein
XP_016507609.1GRF family protein
XP_016507610.1GRF family protein
GRF Family Introduction

Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Kim JH, Choi D, Kende H.
The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis.
Plant J. 2003 Oct;36(1):94-104.
PMID: 12974814