PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Nelumbo nucifera
TCP Family
Species TF ID Description
NNU_000404-RATCP family protein
NNU_000986-RATCP family protein
NNU_001168-RATCP family protein
NNU_002551-RATCP family protein
NNU_002719-RATCP family protein
NNU_003157-RATCP family protein
NNU_004037-RATCP family protein
NNU_006850-RATCP family protein
NNU_007422-RATCP family protein
NNU_008307-RATCP family protein
NNU_009260-RATCP family protein
NNU_012216-RATCP family protein
NNU_019579-RATCP family protein
NNU_020671-RATCP family protein
NNU_022609-RATCP family protein
NNU_026089-RATCP family protein
TCP Family Introduction

The TCP gene family was first described in 1999, as a small group of plant genes encoding proteins sharing the socalled TCP domain, a 59-amino acid basic helix-loop-helix (bHLH) motif that allows DNA binding and protein-protein interactions. This domain was initially identified in four proteins encoded by apparently unrelated genes, from which the name 'TCP' was derived: teosinte branched1 (tb1) from maize (Zea mays), CYCLOIDEA (CYC) from snapdragon (Antirrhinum majus), and the PROLIFERATING CELL FACTORS 1 and 2 (PCF1 and PCF2) from rice (Oryza sativa). The tb1 gene is a major determinant of strong apical dominance in domesticated maize. CYC is involved in the control of floral bilateral symmetry in Antirrhinum. PCF1 and PCF2 are factors that bind to the promoter of the rice PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) gene, which encodes a protein involved in DNA replication and repair, maintenance of chromatin structure, chromosome segregation and cell-cycle progression.

TCP genes have been found in various plant species, and new roles in plant development have been elucidated. These discoveries emphasize the importance of this plant-specific gene family in the evolution and developmental control of plant form.

Martin-Trillo M, Cubas P.
TCP genes: a family snapshot ten years later.
Trends Plant Sci, 2010. 15(1): p. 31-9.
PMID: 19963426