PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Nicotiana benthamiana
GRF Family
Species TF ID Description
Niben101Scf01109g00006.1GRF family protein
Niben101Scf01121g00005.1GRF family protein
Niben101Scf01437g03008.1GRF family protein
Niben101Scf01774g07007.1GRF family protein
Niben101Scf01830g01022.1GRF family protein
Niben101Scf01863g07004.1GRF family protein
Niben101Scf02759g01004.1GRF family protein
Niben101Scf03419g10007.1GRF family protein
Niben101Scf03584g06024.1GRF family protein
Niben101Scf04018g04009.1GRF family protein
Niben101Scf04398g06011.1GRF family protein
Niben101Scf04813g00009.1GRF family protein
Niben101Scf05610g03025.1GRF family protein
Niben101Scf05644g01001.1GRF family protein
Niben101Scf08535g02004.1GRF family protein
Niben101Scf08535g02005.1GRF family protein
Niben101Scf09130g00007.1GRF family protein
Niben101Scf13206g00003.1GRF family protein
Niben101Scf14022g01008.1GRF family protein
Niben101Scf17513g00008.1GRF family protein
GRF Family Introduction

Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Kim JH, Choi D, Kende H.
The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis.
Plant J. 2003 Oct;36(1):94-104.
PMID: 12974814