PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Malus domestica
HB-other Family
Species TF ID Description
MDP0000119866HB-other family protein
MDP0000122897HB-other family protein
MDP0000131659HB-other family protein
MDP0000135389HB-other family protein
MDP0000161239HB-other family protein
MDP0000191575HB-other family protein
MDP0000192108HB-other family protein
MDP0000202143HB-other family protein
MDP0000207866HB-other family protein
MDP0000209424HB-other family protein
MDP0000232860HB-other family protein
MDP0000268133HB-other family protein
MDP0000269415HB-other family protein
MDP0000274554HB-other family protein
MDP0000288192HB-other family protein
MDP0000299774HB-other family protein
MDP0000315095HB-other family protein
MDP0000502194HB-other family protein
MDP0000690933HB-other family protein
HB-other Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

Note: In plantTFDB, proteins of HB-other family include HB superfamily proteins that cannot be classified as HD-ZIP, TALE, WOX and HB-PHD.