PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Musa acuminata
ZF-HD Family
Species TF ID Description
GSMUA_Achr10P11020_001ZF-HD family protein
GSMUA_Achr10P20470_001ZF-HD family protein
GSMUA_Achr10P29790_001ZF-HD family protein
GSMUA_Achr10P30290_001ZF-HD family protein
GSMUA_Achr1P13300_001ZF-HD family protein
GSMUA_Achr2P23010_001ZF-HD family protein
GSMUA_Achr3P16680_001ZF-HD family protein
GSMUA_Achr3P19060_001ZF-HD family protein
GSMUA_Achr3P20390_001ZF-HD family protein
GSMUA_Achr3P31090_001ZF-HD family protein
GSMUA_Achr4P07850_001ZF-HD family protein
GSMUA_Achr4P14910_001ZF-HD family protein
GSMUA_Achr5P05500_001ZF-HD family protein
GSMUA_Achr6P02170_001ZF-HD family protein
GSMUA_Achr6P02700_001ZF-HD family protein
GSMUA_Achr6P17420_001ZF-HD family protein
GSMUA_Achr6P22120_001ZF-HD family protein
GSMUA_Achr6P24230_001ZF-HD family protein
GSMUA_Achr6P27240_001ZF-HD family protein
GSMUA_Achr6P28870_001ZF-HD family protein
GSMUA_Achr6P30650_001ZF-HD family protein
GSMUA_Achr7P19060_001ZF-HD family protein
GSMUA_Achr7P25600_001ZF-HD family protein
GSMUA_Achr8P27010_001ZF-HD family protein
GSMUA_Achr9P08090_001ZF-HD family protein
GSMUA_AchrUn_randomP03390_001ZF-HD family protein
GSMUA_AchrUn_randomP14420_001ZF-HD family protein
ZF-HD Family Introduction

This group of sequences described by a 54-residue domain found in the N-terminal region of plant proteins, the vast majority of which contain a ZF-HD class homeobox domain toward the C terminus. The region between the two domains typically is rich in low complexity sequence. The companion ZF-HD homeobox domain is described in INTERPRO:IPR006455.

A one-hybrid screen resulted in the cloning of four different members of a novel class of plant homeodomain proteins, which are most likely involved in the mesophyll-specific expression of the C4 PEPCase gene in C4 species of the genus Flaveria. Inspection of the homeodomains of the four proteins reveals that they share many common features with homeodomains described so far, but there are also significant differences. Interestingly, this class of homeodomain proteins occurs also in Arabidopsis thaliana and other C3 plants. One-hybrid experiments as well as in vitro DNA binding studies confirmed that these novel homeodomain proteins specifically interact with the proximal region of the C4 PEPCase (C4 phosphoenolpyruvate carboxylase) gene. The N-terminal domains of the homeodomain proteins contain highly conserved sequence motifs. Two-hybrid experiments show that these motifs are sufficient to confer homo- or heterodimer formation between the proteins. Mutagenesis of conserved cysteine residues within the dimerization domain indicates that these residues are essential for dimer formation. Therefore, we designate this novel class of homeobox proteins ZF-HD, for zinc finger homeodomain protein. Our data suggest that the ZF-HD class of homeodomain proteins may be involved in the establishment of the characteristic expression pattern of the C4 PEPCase gene.

Windhovel A, Hein I, Dabrowa R, Stockhaus J.
Characterization of a novel class of plant homeodomain proteins that bind to the C4 phosphoenolpyruvate carboxylase gene of Flaveria trinervia.
Plant Mol Biol. 2001 Jan;45(2):201-14.
PMID: 11289511