PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Linum usitatissimum
TCP Family
Species TF ID Description
Lus10000463TCP family protein
Lus10003078TCP family protein
Lus10008444TCP family protein
Lus10008621TCP family protein
Lus10010177TCP family protein
Lus10013814TCP family protein
Lus10015760TCP family protein
Lus10017856TCP family protein
Lus10019949TCP family protein
Lus10021713TCP family protein
Lus10023297TCP family protein
Lus10032022TCP family protein
Lus10032465TCP family protein
Lus10032984TCP family protein
Lus10034072TCP family protein
Lus10034679TCP family protein
Lus10035055TCP family protein
Lus10035193TCP family protein
Lus10037046TCP family protein
Lus10037190TCP family protein
Lus10038512TCP family protein
Lus10041328TCP family protein
Lus10042962TCP family protein
TCP Family Introduction

The TCP gene family was first described in 1999, as a small group of plant genes encoding proteins sharing the socalled TCP domain, a 59-amino acid basic helix-loop-helix (bHLH) motif that allows DNA binding and protein-protein interactions. This domain was initially identified in four proteins encoded by apparently unrelated genes, from which the name 'TCP' was derived: teosinte branched1 (tb1) from maize (Zea mays), CYCLOIDEA (CYC) from snapdragon (Antirrhinum majus), and the PROLIFERATING CELL FACTORS 1 and 2 (PCF1 and PCF2) from rice (Oryza sativa). The tb1 gene is a major determinant of strong apical dominance in domesticated maize. CYC is involved in the control of floral bilateral symmetry in Antirrhinum. PCF1 and PCF2 are factors that bind to the promoter of the rice PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) gene, which encodes a protein involved in DNA replication and repair, maintenance of chromatin structure, chromosome segregation and cell-cycle progression.

TCP genes have been found in various plant species, and new roles in plant development have been elucidated. These discoveries emphasize the importance of this plant-specific gene family in the evolution and developmental control of plant form.

Martin-Trillo M, Cubas P.
TCP genes: a family snapshot ten years later.
Trends Plant Sci, 2010. 15(1): p. 31-9.
PMID: 19963426